Regular insulin and Demerol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Regular insulin (insulin pork) and Demerol (meperidine hydrochloride). Common drug interactions include acute respiratory distress syndrome among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Regular insulin and Demerol. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Regular insulin?

Regular insulin has active ingredients of insulin pork. It is often used in type 1 diabetes. eHealthMe is studying from 2,848 Regular insulin users. Check the latest studies of Regular insulin.

What is Demerol?

Demerol has active ingredients of meperidine hydrochloride. It is often used in pain. eHealthMe is studying from 12,706 Demerol users. Check the latest studies of Demerol.



On Jul, 17, 2026

15 people who take Regular insulin and Demerol together, and have interactions are studied.

Regular insulin and Demerol drug interactions.

What are the common drug interactions of Regular Insulin and Demerol, by gender? *:

female:

  1. Acute respiratory distress syndrome
  2. Blood bilirubin increased
  3. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  4. Hypotension (abnormally low blood pressure)
  5. Pneumonia respiratory syncytial viral (respiratory syncytial virus (rsv) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children)
  6. Pneumonitis (inflammation of the walls of the alveoli in the lungs)
  7. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  8. Anxiety
  9. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  10. Depression

male:

  1. Cardiac failure congestive
  2. Fluid overload (too much fluid in the blood)
  3. Abdominal discomfort
  4. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
  5. Anaemia (lack of blood)
  6. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  7. Arthralgia (joint pain)
  8. Ascites (accumulation of fluid in the abdominal cavity)
  9. Blood pressure decreased
  10. Cardiac arrest

What are the common drug interactions of Regular Insulin and Demerol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Acute respiratory distress syndrome
  2. Blood bilirubin increased
  3. Hypernatraemia (an abnormally high plasma concentration of sodium ions)
  4. Hypotension (abnormally low blood pressure)
  5. Pneumonia respiratory syncytial viral (respiratory syncytial virus (rsv) is a very common virus that leads to mild, cold-like symptoms in adults and older healthy children)
  6. Pneumonitis (inflammation of the walls of the alveoli in the lungs)

20-29:

n/a

30-39:

  1. Cardiogenic shock (inadequate circulation of blood)
  2. Injury
  3. Psychiatric symptom
  4. Renal failure (kidney dysfunction)

40-49:

  1. Cardiac failure congestive
  2. Fluid overload (too much fluid in the blood)
  3. Rash
  4. Respiratory failure (inadequate gas exchange by the respiratory system)
  5. Sepsis (a severe blood infection that can lead to organ failure and death)
  6. Abdominal pain
  7. Blood pressure decreased
  8. Chest pain
  9. Drug hypersensitivity
  10. Headache (pain in head)

50-59:

  1. Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue)
  2. Anaemia (lack of blood)
  3. Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
  4. Back pain
  5. Chest pain
  6. Chronic obstructive airways disease
  7. Colonic polyp (extra part of colon tissue grow in intestine)
  8. Cor pulmonale (enlargement of the right ventricle of the heart)
  9. Coronary artery atherosclerosis (life-threatening blockages in the arteries of your heart)
  10. Dehydration (dryness resulting from the removal of water)

60+:

  1. Abdominal distension
  2. Abdominal discomfort
  3. Depression
  4. Diarrhoea
  5. Duodenal ulcer perforation (untreated ulcer can burn through the wall of the stomach)
  6. Dyspnoea (difficult or laboured respiration)
  7. Fear
  8. Gastric perforation (hole in stomach)
  9. Injection site irritation
  10. Injury

What are the existing conditions these people have? *

  1. High Blood Pressure: 5 people, 33.33%
  2. Wound: 4 people, 26.67%
  3. Sedation: 4 people, 26.67%
  4. Agitation (state of anxiety or nervous excitement): 4 people, 26.67%
  5. Anaemia (lack of blood): 4 people, 26.67%
  6. Angiopathy (generic term for a disease of the blood vessels): 4 people, 26.67%
  7. Chills (felling of cold): 4 people, 26.67%
  8. Constipation: 4 people, 26.67%
  9. Cough: 4 people, 26.67%
  10. Dry Skin: 4 people, 26.67%

* Approximation only. Some reports may have incomplete information.

Do you take Regular insulin and Demerol?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Regular insulin and Demerol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Regular insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Demerol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Regular insulin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Demerol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on insulin pork and meperidine hydrochloride (the active ingredients of Regular insulin and Demerol, respectively), and Regular insulin and Demerol (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: