Relafen and Solu-medrol drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Relafen (nabumetone) and Solu-medrol (methylprednisolone sodium succinate). Common drug interactions include pulmonary hypertension among females and cardiac failure congestive among males.

The phase IV clinical study analyzes what interactions people have when they take Relafen and Solu-medrol. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Relafen?

Relafen has active ingredients of nabumetone. It is often used in arthritis. eHealthMe is studying from 6,243 Relafen users. Check the latest studies of Relafen.

What is Solu-medrol?

Solu-medrol has active ingredients of methylprednisolone sodium succinate. It is often used in multiple sclerosis. eHealthMe is studying from 39,410 Solu-medrol users. Check the latest studies of Solu-medrol.

On Jul, 17, 2026

15 people who take Relafen and Solu-medrol together, and have interactions are studied.

Relafen and Solu-medrol drug interactions.

What are the common drug interactions of Relafen and Solu-Medrol, by gender? *:

female:

Pulmonary hypertension (increase in blood pressure in the lung artery)
Purulent discharge (discharge that contains pus)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Rectal haemorrhage (bleeding from anus)
Respiratory distress (difficulty in breathing)
Retinal haemorrhage (bleeding from retina)
Rheumatoid arthritis (a chronic progressive disease causing inflammation in the joints)
Salivary gland mass
Spinal column stenosis (narrowing of spinal column)
Spinal osteoarthritis (joint cartilage loss in spine)

male:

Cardiac failure congestive
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hyperlipidaemia (presence of excess lipids in the blood)
Malignant melanoma of skin stage unspecified (cancer of skin un specific stage)
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Myopathy (a muscular disease in which the muscle fibres do not function)

What are the common drug interactions of Relafen and Solu-Medrol, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Completed suicide (act of taking one's own life)

40-49:

Aggression
Arrhythmia (irregular heartbeat)
Bone mass decreased
Cardiomyopathy (weakening of the heart muscle)
Chest pain
Compression fracture (fracture due to pressure caused by injury)
Cushing's syndrome (obesity, a rounded face, increased fat)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dyspnoea (difficult or laboured respiration)

50-59:

Chest pain
Pallor

60+:

Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Hypotension (abnormally low blood pressure)
Aortic arteriosclerosis (hardening of the aortic arteries)
Arteriosclerosis (thickening and hardening of arteries)
Arthralgia (joint pain)
Back disorder
Back pain
Blood pressure increased
Bone disorder
Cardiac failure congestive

What are the existing conditions these people have? *

Sleep Disorder: 1 person, 6.67%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.67%
Quit Smoking: 1 person, 6.67%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 1 person, 6.67%
Hepatitis C: 1 person, 6.67%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 6.67%
Colitis (inflammation of colon): 1 person, 6.67%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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