Remeron and Excedrin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Remeron (mirtazapine) and Excedrin (acetaminophen; aspirin; caffeine). Common drug interactions include dyspnoea among females and loss of consciousness among males.

The phase IV clinical study analyzes what interactions people have when they take Remeron and Excedrin. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Remeron?

Remeron has active ingredients of mirtazapine. It is often used in depression. eHealthMe is studying from 26,475 Remeron users. Check the latest studies of Remeron.

What is Excedrin?

Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. eHealthMe is studying from 22,740 Excedrin users. Check the latest studies of Excedrin.

On Aug, 05, 2026

73 people who take Remeron and Excedrin together, and have interactions are studied.

What are the common drug interactions of Remeron and Excedrin, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Ear infection
Eye infection
Limb injury
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Oropharyngeal pain
Vitamin d decreased
Weight increased
Chest discomfort
Bone fragmentation

male:

Loss of consciousness
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Fatigue (feeling of tiredness)
Loss of libido (loss of sexual urge)
Sexual dysfunction (difficulty experienced by an individual or a couple during any stage of a normal sexual activity)
Sperm concentration decreased
Abdominal pain upper
Arthralgia (joint pain)
Blindness unilateral
Blood sodium decreased

What are the common drug interactions of Remeron and Excedrin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Hepatitis b

30-39:

Asthenia (weakness)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dizziness
Lacunar infarction (a type of stroke)
Abdominal discomfort
Anaemia (lack of blood)
Atelectasis (partial or complete collapse of the lung)
Blood potassium decreased
Bradycardia (abnormally slow heart action)
Cardiac failure congestive

40-49:

Breast mass
Injection site pain
Middle ear effusion (fluid in middle ear)
Psoriatic arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop)
Respiratory tract infection viral
Urinary tract infection
Weight decreased
Anal fissure
Erythema (redness of the skin)
Influenza

50-59:

Mitral valve prolapse (heart's mitral valve doesn't work well)
Oral torus (a lesion made of compact bone and occurs along the palate or the mandible inside the mouth)
Pain in extremity
Postmenopausal haemorrhage (post-menopausal bleeding)
Seasonal affective disorder (a type of depression that occurs at a certain time of the year, usually in the winter)
Uterine disorder
Uterine malposition
Uterine prolapse
Vaginal disorder
Vein disorder

60+:

Dyspnoea (difficult or laboured respiration)
Loss of consciousness
Pneumonia
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Renal failure acute (rapid kidney dysfunction)
Rhabdomyolysis (a condition in which damaged skeletal muscle tissue breaks down)
Abdominal pain lower
Acute respiratory failure
Appendicitis (inflammation of the appendix)
Chronic kidney disease

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 13.70%
Immunodeficiency Common Variable: 9 people, 12.33%
Migraine (headache): 8 people, 10.96%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 8 people, 10.96%
High Blood Pressure: 7 people, 9.59%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.22%
High Blood Cholesterol: 5 people, 6.85%
Back Pain: 5 people, 6.85%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 4 people, 5.48%
Pain: 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

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