Remicade and Keytruda drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Remicade (infliximab) and Keytruda (pembrolizumab). Common drug interactions include insomnia among females and hepatitis among males.

The phase IV clinical study analyzes what interactions people have when they take Remicade and Keytruda. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Remicade?

Remicade has active ingredients of infliximab. It is often used in crohn's disease. eHealthMe is studying from 224,011 Remicade users. Check the latest studies of Remicade.

What is Keytruda?

Keytruda has active ingredients of pembrolizumab. It is often used in renal cell carcinoma. eHealthMe is studying from 57,404 Keytruda users. Check the latest studies of Keytruda.

On Jul, 20, 2026

34 people who take Remicade and Keytruda together, and have interactions are studied.

Remicade and Keytruda drug interactions.

What are the common drug interactions of Remicade and Keytruda, by gender? *:

female:

Insomnia (sleeplessness)
Colitis (inflammation of colon)
Diarrhoea
Adverse reaction
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Gastric perforation (hole in stomach)
Herpes simplex (herpes simplex is a common viral infection)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Infusion related reaction
Malaise (a feeling of general discomfort or uneasiness)

male:

Hepatitis (inflammation of the liver)
Intestinal perforation (complete penetration of the wall of the intestine)
Malignant neoplasm progression (cancer tumour came back)
Pneumonia
Arthralgia (joint pain)
Interstitial lung disease
Acute respiratory distress syndrome
Dyspnoea (difficult or laboured respiration)
Cardiac arrest
Chlamydial infection (a common sexually transmitted infection (sti) in humans caused by the bacterium chlamydia trachomatis)

What are the common drug interactions of Remicade and Keytruda, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Colitis (inflammation of colon)

40-49:

n/a

50-59:

Insomnia (sleeplessness)
Malaise (a feeling of general discomfort or uneasiness)
Nasopharyngitis (inflammation of the nasopharynx)
Vaginal infection
Vulvovaginal mycotic infection (vulvovaginal fungal infection)
Autoimmune arthritis (joint inflammation)
Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Hyperglycaemia (high blood sugar)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Vanishing bile duct syndrome (loose collection of diseases which leads to the injury to hepatic bile ducts and eventual ductopenia)

60+:

Hepatitis (inflammation of the liver)
Respiratory failure (inadequate gas exchange by the respiratory system)
Eyelid ptosis (falling of the upper or lower eyelid)
Muscular weakness (muscle weakness)
Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)
Myocarditis (inflammation of heart muscle myocardium)
Myositis (inflammation of the muscles)
Adverse reaction
Herpes simplex (herpes simplex is a common viral infection)
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)

What are the existing conditions these people have? *

Squamous Cell Carcinoma (a cancer of a kind of epithelial cell): 5 people, 14.71%
Neuralgia (pain in one or more nerves): 5 people, 14.71%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 5 people, 14.71%
High Blood Pressure: 5 people, 14.71%
High Blood Cholesterol: 5 people, 14.71%
Colitis (inflammation of colon): 5 people, 14.71%
Adenocarcinoma (malignant tumour formed from glandular structures in epithelial tissue): 5 people, 14.71%
Lung Cancer - Non-Small Cell (lung cancer): 3 people, 8.82%
Endometrial Cancer: 3 people, 8.82%
Metastatic Bronchial Carcinoma (spread of cancer to bronchi tumour): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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