Abilify and Remodulin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Abilify (aripiprazole) and Remodulin (treprostinil sodium). Common drug interactions include headache among females and chest pain among males.

The phase IV clinical study analyzes what interactions people have when they take Abilify and Remodulin. It is created by eHealthMe based on reports of 49 people who take the same drugs from the FDA, and is updated regularly.

What is Abilify?

Abilify has active ingredients of aripiprazole. It is often used in depression. eHealthMe is studying from 101,450 Abilify users. Check the latest studies of Abilify.

What is Remodulin?

Remodulin has active ingredients of treprostinil sodium. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,842 Remodulin users. Check the latest studies of Remodulin.



On Feb, 11, 2026

49 people who take Abilify and Remodulin together, and have interactions are studied.

Abilify and Remodulin drug interactions.

What are the common drug interactions of Abilify and Remodulin, by gender? *:

female:

  1. Headache (pain in head)
  2. Nausea (feeling of having an urge to vomit)
  3. Dyspnoea (difficult or laboured respiration)
  4. Infusion site erythema (reddening of the skin at infusion site)
  5. Infusion site pain
  6. Infusion site infection
  7. Chest pain
  8. Diarrhoea
  9. Infusion site pruritus (severe itching at infusion site)
  10. Cardiac failure

male:

  1. Chest pain
  2. Death
  3. Diabetes mellitus inadequate control
  4. Disease progression
  5. Ear pain
  6. Glycosuria (excretion of glucose into the urine)
  7. Pancreatitis (inflammation of pancreas)
  8. Pancreatitis acute (sudden inflammation of pancreas)
  9. Pulmonary hypertension (increase in blood pressure in the lung artery)
  10. Type 2 diabetes mellitus

What are the common drug interactions of Abilify and Remodulin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Blood cholesterol increased
  2. Blood triglycerides increased
  3. Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
  4. Death
  5. Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
  6. Hyperlipidaemia (presence of excess lipids in the blood)
  7. Insulin resistance
  8. Type 1 diabetes mellitus
  9. Type 2 diabetes mellitus
  10. Weight increased

30-39:

  1. Diarrhoea
  2. Haematemesis (vomiting of blood)
  3. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  4. Nausea (feeling of having an urge to vomit)
  5. Pain
  6. Platelet count decreased
  7. Prerenal failure
  8. Sepsis (a severe blood infection that can lead to organ failure and death)
  9. Therapeutic response decreased (less preventive response)
  10. Vomiting

40-49:

  1. Atelectasis (partial or complete collapse of the lung)
  2. Chest discomfort
  3. Death
  4. Device related infection
  5. Headache (pain in head)
  6. Hypoxia (low oxygen in tissues)
  7. Infusion site infection
  8. Iron deficiency anaemia
  9. Klebsiella bacteraemia (klebsiella bacteria in blood after infection to lungs)
  10. Pleural effusion (water on the lungs)

50-59:

  1. Headache (pain in head)
  2. Nausea (feeling of having an urge to vomit)
  3. Cardiac failure
  4. Dyspnoea (difficult or laboured respiration)
  5. Infusion site erythema (reddening of the skin at infusion site)
  6. Infusion site induration
  7. Infusion site infection
  8. Infusion site pain
  9. Infusion site pruritus (severe itching at infusion site)
  10. Infusion site warmth

60+:

  1. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  2. Fluid retention (an abnormal accumulation of fluid in the blood)
  3. Tenderness (pain or discomfort when an affected area is touched)
  4. Cellulitis (infection under the skin)
  5. Death
  6. Erythema (redness of the skin)
  7. Malaise (a feeling of general discomfort or uneasiness)
  8. Maternal exposure during pregnancy (use of substance during pregnancy)
  9. Normal newborn
  10. Oedema peripheral (superficial swelling)

What are the existing conditions these people have? *

  1. Pulmonary Hypertension (increase in blood pressure in the lung artery): 6 people, 12.24%
  2. High Blood Pressure: 5 people, 10.20%
  3. Anaemia (lack of blood): 5 people, 10.20%
  4. Allergic Rhinitis: 5 people, 10.20%
  5. Urination - Excessive Volume: 4 people, 8.16%
  6. Joint Pain: 4 people, 8.16%

* Approximation only. Some reports may have incomplete information.

Do you take Abilify and Remodulin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Abilify and Remodulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Abilify:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Remodulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Abilify and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Remodulin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on aripiprazole and treprostinil sodium (the active ingredients of Abilify and Remodulin, respectively), and Abilify and Remodulin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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