Renagel and Prandin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Renagel (sevelamer hydrochloride) and Prandin (repaglinide). Common drug interactions include asthenia among females and nephrogenic systemic fibrosis among males.

The phase IV clinical study analyzes what interactions people have when they take Renagel and Prandin. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Prandin?

Prandin has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 4,680 Prandin users. Check the latest studies of Prandin.

On Jul, 25, 2026

22 people who take Renagel and Prandin together, and have interactions are studied.

What are the common drug interactions of Renagel and Prandin, by gender? *:

female:

Asthenia (weakness)
Dry skin
Fatigue (feeling of tiredness)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Joint stiffness
Joint swelling
Muscle tightness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Myalgia (muscle pain)
Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

male:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Muscle tightness
Oedema (fluid collection in tissue)
Oedema peripheral (superficial swelling)
Pain
Pneumonia
Pruritus (severe itching of the skin)
Rash
Renal failure chronic (long lasting kidney dysfunction)

What are the common drug interactions of Renagel and Prandin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anxiety
Asthenia (weakness)
Dry skin
Erythema (redness of the skin)
Gait disturbance
Injury
Joint range of motion decreased (disease of joint movement)
Muscle tightness

60+:

Asthenia (weakness)
Dry skin
Nodule on extremity (a small rock or mineral cluster on hands or legs)
Oedema (fluid collection in tissue)
Pain in extremity
Pruritus (severe itching of the skin)
Rash papular (redness with papule)
Skin hyperpigmentation (disorders affect the colour of your skin)
Skin hypertrophy (skin cells enlarges)
Skin tightness

What are the existing conditions these people have? *

Hyperphosphataemia (electrolyte disturbance in which there is an abnormally elevated level of phosphate in the blood): 2 people, 9.09%
Conjunctivitis (pink eye): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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