Repaglinide and Olmetec drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Repaglinide (repaglinide) and Olmetec (olmesartan medoxomil). Common drug interactions include confusional state among females and pancreatitis acute among males.
The phase IV clinical study analyzes what interactions people have when they take Repaglinide and Olmetec. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.
What is Repaglinide?
Repaglinide has active ingredients of repaglinide. It is often used in diabetes. eHealthMe is studying from 8,226 Repaglinide users. Check the latest studies of Repaglinide.
What is Olmetec?
Olmetec has active ingredients of olmesartan medoxomil. It is often used in high blood pressure. eHealthMe is studying from 7,904 Olmetec users. Check the latest studies of Olmetec.
21 people who take Repaglinide and Olmetec together, and have interactions are studied.

What are the common drug interactions of Repaglinide and Olmetec, by gender? *:
female:
- Confusional state
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- International normalised ratio increased
- Lethargy (tiredness)
- Oral mucosa erosion (erosion of mouth mucous membrane)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Cardiac failure chronic
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Sopor (sleep)
male:
- Pancreatitis acute (sudden inflammation of pancreas)
- Dyspnoea (difficult or laboured respiration)
- Hypokinesia (decreased bodily movement)
- Hypoxic-ischaemic encephalopathy (a condition that occurs when the entire brain is deprived of an adequate oxygen supply, but the deprivation isn't total)
- Loss of consciousness
- Pulmonary congestion (congestion in the lungs)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Stress cardiomyopathy (stress-induced chronic disease of the heart muscle)
- Ventricular hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do)
- Alanine aminotransferase increased
What are the common drug interactions of Repaglinide and Olmetec, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Oral mucosa erosion (erosion of mouth mucous membrane)
- Palmar-plantar erythrodysaesthesia syndrome (hand-foot syndrome)
- Back pain
- Pancreatitis acute (sudden inflammation of pancreas)
- Prostatomegaly (enlargement of the prostate)
50-59:
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Pancreatitis acute (sudden inflammation of pancreas)
- Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
- Akinesia (loss of control of voluntary muscle movements)
- Arrhythmia (irregular heartbeat)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Cerebral disorder (brain disease)
- Dyspnoea (difficult or laboured respiration)
- Heart rate increased
- Hyperkinetic heart syndrome (hyperkinetic heart disease is when the heart is beating faster that it should be)
60+:
- Alanine aminotransferase increased
- Aspartate aminotransferase increased
- Myocarditis (inflammation of heart muscle myocardium)
- Pneumonia
- Prothrombin time ratio decreased
- Anuria (failure of the kidneys to produce urine)
- Cardiac failure chronic
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Dyspnoea (difficult or laboured respiration)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
What are the existing conditions these people have? *
- Type 2 Diabetes: 10 people, 47.62%
- Pain: 4 people, 19.05%
- Gouty Arthritis (joint inflammation with crystal formation): 4 people, 19.05%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 19.05%
- Cardiac Failure Congestive: 3 people, 14.29%
- Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 2 people, 9.52%
* Approximation only. Some reports may have incomplete information.
Do you take Repaglinide and Olmetec?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Repaglinide (8,226 reports)
- Olmetec (7,904 reports)
Browse all drug interactions of Repaglinide and Olmetec:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Repaglinide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Olmetec:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Repaglinide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Olmetec and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on repaglinide and olmesartan medoxomil (the active ingredients of Repaglinide and Olmetec, respectively), and Repaglinide and Olmetec (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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