Repatha and Adderall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Repatha (evolocumab) and Adderall (amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate). Common drug interactions include gait disturbance among females and sinusitis among males.

The phase IV clinical study analyzes what interactions people have when they take Repatha and Adderall. It is created by eHealthMe based on reports of 53 people who take the same drugs from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Adderall?

Adderall has active ingredients of amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 64,224 Adderall users. Check the latest studies of Adderall.



On Jul, 07, 2026

53 people who take Repatha and Adderall together, and have interactions are studied.

Repatha and Adderall drug interactions.

What are the common drug interactions of Repatha and Adderall, by gender? *:

female:

  1. Gait disturbance
  2. Gastric ph decreased
  3. Hypertension (high blood pressure)
  4. Hypokalaemia (low potassium)
  5. Hypotension (abnormally low blood pressure)
  6. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  7. Injection site pain
  8. Intervertebral disc degeneration (spinal disc degeneration)
  9. Irritability
  10. Joint injury

male:

  1. Sinusitis (inflammation of sinus)
  2. Pain
  3. Surgery
  4. Urinary tract infection
  5. Wrist surgery
  6. Abnormal dreams
  7. Asthenia (weakness)
  8. Back pain
  9. Delusion (a false belief or opinion)
  10. Diarrhoea

What are the common drug interactions of Repatha and Adderall, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Tooth abscess (pus formation in tooth)

50-59:

  1. Diarrhoea
  2. Headache (pain in head)
  3. Anxiety
  4. Disturbance in attention
  5. Parotitis (inflammation of a parotid gland)
  6. Sialoadenitis (inflammation of a salivary gland)
  7. Sinusitis (inflammation of sinus)
  8. Upper-airway cough syndrome
  9. Urinary tract infection
  10. Anger

60+:

  1. Asthenia (weakness)
  2. Back pain
  3. Pain in extremity
  4. Parainfluenzae virus infection
  5. Peripheral swelling
  6. Pneumonia
  7. Sinus congestion (blockage of sinus)
  8. Sinusitis (inflammation of sinus)
  9. Blood creatinine increased
  10. Blood testosterone increased

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 20 people, 37.74%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 20.75%
  3. Stress And Anxiety: 4 people, 7.55%
  4. Drowsiness: 4 people, 7.55%
  5. Depression: 4 people, 7.55%
  6. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 5.66%
  7. Hiv Infection: 3 people, 5.66%
  8. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 5.66%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and Adderall?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Repatha and Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Adderall:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Repatha and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Adderall and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab and amphetamine aspartate; amphetamine sulfate; dextroamphetamine saccharate; dextroamphetamine sulfate (the active ingredients of Repatha and Adderall, respectively), and Repatha and Adderall (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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