Repatha and Celecoxib drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Repatha (evolocumab) and Celecoxib (celecoxib). Common drug interactions include low density lipoprotein decreased among females and arthralgia among males.
The phase IV clinical study analyzes what interactions people have when they take Repatha and Celecoxib. It is created by eHealthMe based on reports of 59 people who take the same drugs from the FDA, and is updated regularly.
What is Repatha?
Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.
What is Celecoxib?
Celecoxib has active ingredients of celecoxib. It is often used in arthritis. eHealthMe is studying from 38,217 Celecoxib users. Check the latest studies of Celecoxib.
59 people who take Repatha and Celecoxib together, and have interactions are studied.

What are the common drug interactions of Repatha and Celecoxib, by gender? *:
female:
- Low density lipoprotein decreased (cholesterol decreased)
- Rash
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Diarrhoea
- Drug hypersensitivity
- Drug ineffective
- Fall
- Flatulence (flatus expelled through the anus)
- Hip arthroplasty
- Hypotension (abnormally low blood pressure)
male:
- Arthralgia (joint pain)
- Fatigue (feeling of tiredness)
- Arrhythmia (irregular heartbeat)
- Asthma
- Back pain
- Blood pressure fluctuation
- Bone pain
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Chest pain
- Cystitis (inflammation of the wall of the bladder)
What are the common drug interactions of Repatha and Celecoxib, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
- Anxiety
- Disturbance in attention
- Drug ineffective
- Feeling jittery
- Initial insomnia (feeling of inadequate or poor-quality sleep)
- Nightmare (unpleasant dream)
- Paradoxical drug reaction
- Sleep disorder
40-49:
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
50-59:
- Fatigue (feeling of tiredness)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Death
- Infection
- Pyrexia (fever)
60+:
- Fall
- Dyspnoea (difficult or laboured respiration)
- Hip arthroplasty
- Hypotension (abnormally low blood pressure)
- Injection site erythema (redness at injection site)
- Loss of consciousness
- Muscle spasms (muscle contraction)
- Acute myocardial infarction (acute heart attack)
- Arthralgia (joint pain)
- Asthenia (weakness)
What are the existing conditions these people have? *
- Hyperlipidaemia (presence of excess lipids in the blood): 14 people, 23.73%
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 6.78%
* Approximation only. Some reports may have incomplete information.
Do you take Repatha and Celecoxib?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Repatha and Celecoxib:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Repatha:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Celecoxib:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Repatha and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Celecoxib and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on evolocumab and celecoxib (the active ingredients of Repatha and Celecoxib, respectively), and Repatha and Celecoxib (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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