Repatha and Flovent drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Repatha (evolocumab) and Flovent (fluticasone propionate). Common drug interactions include blood pressure diastolic decreased among females and influenza like illness among males.
The phase IV clinical study analyzes what interactions people have when they take Repatha and Flovent. It is created by eHealthMe based on reports of 65 people who take the same drugs from the FDA, and is updated regularly.
What is Repatha?
Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.
What is Flovent?
Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.
65 people who take Repatha and Flovent together, and have interactions are studied.

What are the common drug interactions of Repatha and Flovent, by gender? *:
female:
- Blood pressure diastolic decreased
- Device related infection
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Cardiac failure congestive
- Intracardiac thrombus (presence of a circumscribed mass with heart wall)
- Mitral valve incompetence (inefficient heart valve)
- Post procedural infection
- Postoperative wound infection
- Renal failure (kidney dysfunction)
- Oxygen saturation decreased
male:
- Influenza like illness
- Asthenia (weakness)
- Hypersensitivity
- Malaise (a feeling of general discomfort or uneasiness)
- Nausea (feeling of having an urge to vomit)
- Pyrexia (fever)
- Vomiting
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
- Prostate cancer
What are the common drug interactions of Repatha and Flovent, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Blood pressure diastolic decreased
- Device related infection
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Cardiac failure congestive
- Intracardiac thrombus (presence of a circumscribed mass with heart wall)
- Mitral valve incompetence (inefficient heart valve)
- Post procedural infection
- Postoperative wound infection
- Renal failure (kidney dysfunction)
- Dyspnoea (difficult or laboured respiration)
50-59:
- Dyspnoea (difficult or laboured respiration)
- Oropharyngeal pain
- Blood parathyroid hormone increased
- Drug ineffective
- Hospitalisation
- Death
- Immune system disorder
60+:
- Hospitalisation
- Arthralgia (joint pain)
- Hypoaesthesia oral (reduced sense of touch or sensation in mouth)
- Influenza like illness
- Lip swelling
- Pain
- Swelling face
- Upper respiratory tract infection
- Abdominal pain lower
- Angina pectoris (chest pain due to ischemia of the heart muscle)
What are the existing conditions these people have? *
- Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 30 people, 46.15%
- Pain: 12 people, 18.46%
- Lung Disorder (lung disease): 7 people, 10.77%
- Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 10.77%
* Approximation only. Some reports may have incomplete information.
Do you take Repatha and Flovent?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Repatha and Flovent:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Repatha:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flovent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Repatha and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flovent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on evolocumab and fluticasone propionate (the active ingredients of Repatha and Flovent, respectively), and Repatha and Flovent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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