Repatha and Revlimid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Repatha (evolocumab) and Revlimid (lenalidomide). Common drug interactions include tenderness among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Repatha and Revlimid. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,258 Repatha users. Check the latest studies of Repatha.

What is Revlimid?

Revlimid has active ingredients of lenalidomide. It is often used in multiple myeloma. eHealthMe is studying from 378,026 Revlimid users. Check the latest studies of Revlimid.



On Aug, 12, 2026

82 people who take Repatha and Revlimid together, and have interactions are studied.

Repatha and Revlimid drug interactions.

What are the common drug interactions of Repatha and Revlimid, by gender? *:

female:

  1. Tenderness (pain or discomfort when an affected area is touched)
  2. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  3. Cough
  4. Creatinine renal clearance increased
  5. Dysgeusia (disorder of the sense of taste)
  6. Feeding disorder (when children refuse to eat certain food groups)
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
  9. Pain
  10. Pancreatic disorder

male:

  1. Diarrhoea
  2. Fatigue (feeling of tiredness)
  3. Cardiac disorder
  4. Death
  5. Dyspnoea (difficult or laboured respiration)
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Restless legs syndrome (a powerful urge to move your legs)
  8. Tremor (trembling or shaking movements in one or more parts of your body)
  9. Cardiac failure congestive
  10. General physical health deterioration (weak health status)

What are the common drug interactions of Repatha and Revlimid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Sinusitis (inflammation of sinus)
  2. Cough
  3. Creatinine renal clearance increased
  4. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  5. Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)

60+:

  1. Diarrhoea
  2. Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
  3. Cellulitis (infection under the skin)
  4. Fatigue (feeling of tiredness)
  5. Myalgia (muscle pain)
  6. Peripheral swelling
  7. Rash
  8. Rash pruritic (redness with itching)
  9. Asthenia (weakness)
  10. Cardiac disorder

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and Revlimid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Repatha and Revlimid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Revlimid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Repatha and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Revlimid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab and lenalidomide (the active ingredients of Repatha and Revlimid, respectively), and Repatha and Revlimid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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