Replavite and Folic acid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Replavite (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e) and Folic acid (folic acid). Common drug interactions include thrombosis among females and diarrhoea among males.

The phase IV clinical study analyzes what interactions people have when they take Replavite and Folic acid. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Replavite?

Replavite has active ingredients of ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e. eHealthMe is studying from 279 Replavite users. Check the latest studies of Replavite.

What is Folic acid?

Folic acid has active ingredients of folic acid. It is often used in rheumatoid arthritis. eHealthMe is studying from 165,027 Folic acid users. Check the latest studies of Folic acid.



On Aug, 13, 2026

17 people who take Replavite and Folic acid together, and have interactions are studied.

Replavite and Folic acid drug interactions.

What are the common drug interactions of Replavite and Folic Acid, by gender? *:

female:

  1. Thrombosis (formation of a blood clot inside a blood vessel)
  2. Decreased appetite
  3. Fatigue (feeling of tiredness)
  4. Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
  5. Hypotension (abnormally low blood pressure)
  6. Infusion site pain
  7. Infusion site swelling
  8. Synovial cyst (cyst of joint filled with synovial fluid)
  9. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  10. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

male:

  1. Diarrhoea
  2. Asthenia (weakness)
  3. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  4. Fatigue (feeling of tiredness)
  5. Hepatic enzyme increased
  6. Hypersensitivity
  7. Injection site pain
  8. Injection site pruritus (severe itching at injection site)
  9. Lung infection
  10. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)

What are the common drug interactions of Replavite and Folic Acid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Aplasia pure red cell (type of anaemia affecting the precursors to red blood cells but not to white blood cells)
  2. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  3. Drug ineffective
  4. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  5. Abdominal pain upper
  6. Blood pressure systolic increased

30-39:

  1. Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

40-49:

n/a

50-59:

  1. Diarrhoea
  2. Asthenia (weakness)
  3. Bacterial test positive
  4. Blood potassium decreased
  5. Blood pressure increased
  6. Blood pressure systolic increased
  7. Dehydration (dryness resulting from the removal of water)
  8. Dyspnoea (difficult or laboured respiration)
  9. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  10. Fatigue (feeling of tiredness)

60+:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Cystitis (inflammation of the wall of the bladder)
  3. Synovial cyst (cyst of joint filled with synovial fluid)
  4. Thrombosis (formation of a blood clot inside a blood vessel)
  5. Renal cancer (cancer of kidney)
  6. Asthenia (weakness)
  7. Blood albumin decreased
  8. Clostridium test positive
  9. Drug hypersensitivity
  10. Heart rate irregular

What are the existing conditions these people have? *

  1. Vipoma (endocrine tumour): 3 people, 17.65%
  2. Joint Pain: 3 people, 17.65%
  3. Blood Phosphorus Abnormal: 3 people, 17.65%
  4. Blood Potassium Decreased: 3 people, 17.65%
  5. Cardiac Disorder: 3 people, 17.65%
  6. Chronic Renal Failure (kidney failure): 3 people, 17.65%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 17.65%
  8. High Blood Pressure: 3 people, 17.65%
  9. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 3 people, 17.65%
  10. Iron Deficiency: 3 people, 17.65%

* Approximation only. Some reports may have incomplete information.

Do you take Replavite and Folic acid?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Replavite and Folic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Replavite:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Folic acid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Replavite and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Folic acid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e and folic acid (the active ingredients of Replavite and Folic acid, respectively), and Replavite and Folic acid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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