Requip and Serax drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Requip (ropinirole hydrochloride) and Serax (oxazepam). Common drug interactions include fall among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Requip and Serax. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

What is Serax?

Serax has active ingredients of oxazepam. It is often used in stress and anxiety. eHealthMe is studying from 1,542 Serax users. Check the latest studies of Serax.



On Aug, 09, 2026

11 people who take Requip and Serax together, and have interactions are studied.

Requip and Serax drug interactions.

What are the common drug interactions of Requip and Serax, by gender? *:

female:

  1. Fall
  2. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  3. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  4. Urinary tract infection
  5. Bladder dysfunction
  6. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)
  9. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  10. Bladder disorder

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Bankruptcy
  3. Fall
  4. Hyperbilirubinaemia (excess of bilirubin in the blood)
  5. Injury
  6. Irritability
  7. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  8. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
  9. Pain
  10. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

What are the common drug interactions of Requip and Serax, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Fall
  2. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  3. Progressive multifocal leukoencephalopathy (rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells)
  4. Urinary tract infection
  5. Bladder dysfunction
  6. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  7. Respiratory failure (inadequate gas exchange by the respiratory system)
  8. Opportunistic infection (a microorganism that normally does not cause disease but becomes pathogenic when the body's immune system is impaired and unable to fight)
  9. Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
  10. Bladder disorder

60+:

  1. Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
  2. Bladder dysfunction
  3. Sedation
  4. Sleep attacks
  5. Urinary tract infection
  6. Fall
  7. Hyperbilirubinaemia (excess of bilirubin in the blood)
  8. Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
  9. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  10. Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)

What are the existing conditions these people have? *

  1. Sleep Disorder: 9 people, 81.82%
  2. Depression: 9 people, 81.82%
  3. Fibromyalgia (a long-term condition which causes pain all over the body): 9 people, 81.82%
  4. Pain: 8 people, 72.73%
  5. Neurogenic Bladder (the normal function of the bladder is to store and empty urine in a coordinated, controlled fashion): 8 people, 72.73%
  6. Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 8 people, 72.73%
  7. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 8 people, 72.73%
  8. Migraine (headache): 8 people, 72.73%
  9. Cystitis Interstitial (unknown cause characterized by bladder pain): 8 people, 72.73%
  10. High Blood Cholesterol: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Requip and Serax?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Requip and Serax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Requip:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Serax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Requip and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Serax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on ropinirole hydrochloride and oxazepam (the active ingredients of Requip and Serax, respectively), and Requip and Serax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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