Restasis and Cefuroxime drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Cefuroxime (cefuroxime sodium). Common drug interactions include fatigue among females and injection site pain among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Cefuroxime. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Cefuroxime?

Cefuroxime has active ingredients of cefuroxime sodium. It is often used in sinusitis. eHealthMe is studying from 12,999 Cefuroxime users. Check the latest studies of Cefuroxime.



On Jul, 12, 2026

54 people who take Restasis and Cefuroxime together, and have interactions are studied.

Restasis and Cefuroxime drug interactions.

What are the common drug interactions of Restasis and Cefuroxime, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Anxiety
  3. Arrhythmia (irregular heartbeat)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Chills (felling of cold)
  6. Confusional state
  7. Decreased appetite
  8. Decubitus ulcer (a chronic ulcer of the skin caused by prolonged pressure on it)
  9. Dehydration (dryness resulting from the removal of water)
  10. Drug dependence

male:

  1. Injection site pain

What are the common drug interactions of Restasis and Cefuroxime, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. American trypanosomiasis (american trypanosomiasis, is caused by infection with the protozoan parasite trypanosoma cruzi)
  2. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  3. Fatigue (feeling of tiredness)
  4. Gingival disorder (gum disease)
  5. Lyme disease (a bacterial infection that is spread to humans by infected ticks)
  6. Myalgia (muscle pain)
  7. Pemphigoid (tense blisters on the skin)
  8. Rocky mountain spotted fever (fever is caused by rickettsia rickettsii a tick bite fever)
  9. Visual impairment

40-49:

  1. Drug ineffective
  2. Gout (uric acid crystals building up in the body)
  3. Hypoaesthesia (reduced sense of touch or sensation)
  4. Influenza
  5. Peripheral swelling

50-59:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal failure (kidney dysfunction)
  4. Renal injury (kidney injury)
  5. Accident
  6. Dizziness
  7. Dysarthria (speech disorder)
  8. Dystonia (abnormal muscle tone)
  9. Emotional disorder
  10. Extrapyramidal disorder (involuntary muscle spasms in the face and neck)

60+:

  1. Diarrhoea
  2. Activities of daily living impaired
  3. Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
  4. Immobile (not moving)
  5. Lethargy (tiredness)
  6. Nausea (feeling of having an urge to vomit)
  7. Nephrosclerosis (hardening of the kidney due to renovascular disease)
  8. Nodal rhythm (40-50 beats per minute)
  9. Overdose
  10. Speech disorder

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 9 people, 16.67%
  2. Immunodeficiency Common Variable: 7 people, 12.96%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 12.96%
  4. Pain: 7 people, 12.96%
  5. Infection: 5 people, 9.26%
  6. High Blood Cholesterol: 5 people, 9.26%
  7. Stress And Anxiety: 5 people, 9.26%
  8. Urinary Tract Infection: 5 people, 9.26%
  9. Immunodeficiency: 4 people, 7.41%
  10. Hypersensitivity: 4 people, 7.41%

* Approximation only. Some reports may have incomplete information.

Do you take Restasis and Cefuroxime?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Restasis and Cefuroxime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Restasis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Cefuroxime:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Restasis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cefuroxime and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine and cefuroxime sodium (the active ingredients of Restasis and Cefuroxime, respectively), and Restasis and Cefuroxime (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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