Restasis and Firazyr drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Restasis (cyclosporine) and Firazyr (icatibant acetate). Common drug interactions include malaise among females and infusion site erythema among males.
The phase IV clinical study analyzes what interactions people have when they take Restasis and Firazyr. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Restasis?
Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.
What is Firazyr?
Firazyr has active ingredients of icatibant acetate. eHealthMe is studying from 5,650 Firazyr users. Check the latest studies of Firazyr.
28 people who take Restasis and Firazyr together, and have interactions are studied.

What are the common drug interactions of Restasis and Firazyr, by gender? *:
female:
- Malaise (a feeling of general discomfort or uneasiness)
- Migraine (headache)
- Muscle spasms (muscle contraction)
- Respiratory disorder (respiratory disease)
- Sinusitis (inflammation of sinus)
- Upper respiratory tract infection
- Vomiting
- Lactose intolerance (inability to digest lactose)
- Obstruction
- Lumbar vertebral fracture
male:
- Infusion site erythema (reddening of the skin at infusion site)
- Infusion site pruritus (severe itching at infusion site)
- Injection site bruising
What are the common drug interactions of Restasis and Firazyr, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Drug ineffective
- Hereditary angioedema (recurrent episodes of severe swelling)
- Abdominal discomfort
- Arthralgia (joint pain)
- Asthenia (weakness)
- Chronic fatigue syndrome (disorder that causes extreme fatigue)
- Diarrhoea
- Fatigue (feeling of tiredness)
- Injection site erythema (redness at injection site)
- Nausea (feeling of having an urge to vomit)
50-59:
- Depressed mood
- Eye infection
- Upper respiratory tract infection
- Vomiting
- Infection
- Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
- Concussion (short loss of normal brain function in response to a head injury)
- Memory impairment
- Balance disorder
- Gait disturbance
60+:
n/a
What are the existing conditions these people have? *
- Immune System Disorder: 18 people, 64.29%
- Hereditary Angioedema (recurrent episodes of severe swelling): 16 people, 57.14%
- Immunodeficiency Common Variable: 5 people, 17.86%
- Heart Attack: 3 people, 10.71%
* Approximation only. Some reports may have incomplete information.
Do you take Restasis and Firazyr?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Restasis and Firazyr:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Restasis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Firazyr:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Restasis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Firazyr and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on cyclosporine and icatibant acetate (the active ingredients of Restasis and Firazyr, respectively), and Restasis and Firazyr (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
Recent studies on eHealthMe:
- Could Advair Diskus 100/50 cause Dissociation? - 3 seconds ago
- Could Pronestyl cause Atrial Fibrillation Aggravated? - 9 seconds ago
- Could Biotin cause Atrial Fibrillation/Flutter? - 14 seconds ago
- Memory Loss and Intervertebral Disc Degeneration - 19 seconds ago
- Drug interactions of Levonorgestrel and Azathioprine - 21 seconds ago
- Drug interactions of Nplate and Heparin - 26 seconds ago
- Could Alocril cause Gastroesophageal Reflux Disease? - 27 seconds ago
- Drug interactions of Levofloxacin and Augmentin '125' - 38 seconds ago
- Drug interactions of Austedo and Spironolactone - 39 seconds ago
- Drug interactions of Levetiracetam and Humira - 43 seconds ago