Restasis and Venclexta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restasis (cyclosporine) and Venclexta (venetoclax). Common drug interactions include syncope among females and death among males.

The phase IV clinical study analyzes what interactions people have when they take Restasis and Venclexta. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Venclexta?

Venclexta has active ingredients of venetoclax. eHealthMe is studying from 31,425 Venclexta users. Check the latest studies of Venclexta.



On Jul, 16, 2026

63 people who take Restasis and Venclexta together, and have interactions are studied.

Restasis and Venclexta drug interactions.

What are the common drug interactions of Restasis and Venclexta, by gender? *:

female:

  1. Syncope (loss of consciousness with an inability to maintain postural tone)
  2. Tooth loss
  3. Urinary tract infection
  4. Visual impairment
  5. Weight decreased
  6. Fatigue (feeling of tiredness)
  7. Diarrhoea
  8. Pyrexia (fever)
  9. White blood cell count decreased
  10. Agitation (state of anxiety or nervous excitement)

male:

  1. Death
  2. White blood cell count decreased
  3. Hospitalisation
  4. Neutropenia (an abnormally low number of neutrophils)
  5. Blood creatinine increased
  6. Dehydration (dryness resulting from the removal of water)
  7. Epistaxis (bleed from the nose)
  8. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  9. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
  10. Hepatic enzyme increased

What are the common drug interactions of Restasis and Venclexta, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Death

50-59:

  1. Death
  2. Bone density decreased
  3. Cardiac disorder
  4. Dermatitis allergic (inflammation of the skin due allergic reaction)
  5. Diarrhoea
  6. Dizziness
  7. Gastrointestinal motility disorder (abnormal intestinal contractions)
  8. Haemorrhage (bleeding)
  9. Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium)
  10. Hypertension (high blood pressure)

60+:

  1. White blood cell count decreased
  2. Death
  3. Cataract (clouding of the lens inside the eye)
  4. Disease progression
  5. Neutropenia (an abnormally low number of neutrophils)
  6. Abdominal pain upper
  7. Blood creatinine increased
  8. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  9. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  10. Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)

What are the existing conditions these people have? *

  1. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 28 people, 44.44%
  2. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 15 people, 23.81%
  3. Pain: 7 people, 11.11%
  4. High Blood Pressure: 5 people, 7.94%
  5. Depression: 5 people, 7.94%
  6. Waldenstrom's Macroglobulinaemia (cancer affects small lymphocytes (white blood cells)): 4 people, 6.35%
  7. Nausea And Vomiting: 4 people, 6.35%
  8. Nausea (feeling of having an urge to vomit): 4 people, 6.35%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 4 people, 6.35%

* Approximation only. Some reports may have incomplete information.

Do you take Restasis and Venclexta?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Restasis and Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Restasis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Venclexta:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Restasis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Venclexta and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine and venetoclax (the active ingredients of Restasis and Venclexta, respectively), and Restasis and Venclexta (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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