Restoril and Gilenya drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Restoril (temazepam) and Gilenya (fingolimod). Common drug interactions include dyskinesia among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Restoril and Gilenya. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Restoril?

Restoril has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 13,522 Restoril users. Check the latest studies of Restoril.

What is Gilenya?

Gilenya has active ingredients of fingolimod. It is often used in multiple sclerosis. eHealthMe is studying from 111,893 Gilenya users. Check the latest studies of Gilenya.

On Aug, 03, 2026

91 people who take Restoril and Gilenya together, and have interactions are studied.

What are the common drug interactions of Restoril and Gilenya, by gender? *:

female:

Dyskinesia (abnormality or impairment of voluntary movement)
Hypertension (high blood pressure)
Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition)
Nasopharyngitis (inflammation of the nasopharynx)
Protein total increased
Speech disorder
Swelling face
Blood alkaline phosphatase decreased
Blood urea increased
Cavernous sinus thrombosis (formation of a blood clot in brain)

male:

Fatigue (feeling of tiredness)
Hypertension (high blood pressure)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Depression
Dizziness
Drug hypersensitivity
Fall
Gait disturbance
General physical health deterioration (weak health status)
Hangover

What are the common drug interactions of Restoril and Gilenya, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Anxiety
Hemiplegia (paralysis of one side of the body)
Back pain
Decreased appetite
Depression
Disturbance in attention
Hypoaesthesia (reduced sense of touch or sensation)
Memory impairment
Oedema peripheral (superficial swelling)
Protein total increased

30-39:

Nausea (feeling of having an urge to vomit)
Depression
Vomiting
Anaemia (lack of blood)
Aphasia (damage to the parts of the brain that control language)
Back pain
Blood chloride increased
Blood iron decreased
Carbon dioxide decreased
Cardiac arrest

40-49:

Hypoaesthesia (reduced sense of touch or sensation)
Anxiety
Heart rate increased
Blood pressure increased
Miliaria (a skin disease marked by small and itchy rashes)
Palpitations (feelings or sensations that your heart is pounding or racing)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Fatigue (feeling of tiredness)
Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Gait disturbance

50-59:

Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Confusional state
Cough
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Dizziness
Drug ineffective
Drug intolerance (drug sensitivity)
Ear infection
Hypoaesthesia (reduced sense of touch or sensation)
Hypotension (abnormally low blood pressure)

60+:

Blood pressure increased
Fatigue (feeling of tiredness)
Bladder disorder
Cardiac failure congestive
Cough
Dyspnoea (difficult or laboured respiration)
Femur fracture
Full blood count decreased
Haemorrhage (bleeding)
Headache (pain in head)

What are the existing conditions these people have? *

Headache (pain in head): 11 people, 12.09%
Stress And Anxiety: 10 people, 10.99%
High Blood Pressure: 10 people, 10.99%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 8 people, 8.79%
Pain: 7 people, 7.69%
Fatigue (feeling of tiredness): 7 people, 7.69%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 6 people, 6.59%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 5.49%
Migraine (headache): 5 people, 5.49%
Hypersensitivity: 5 people, 5.49%

* Approximation only. Some reports may have incomplete information.

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