Revatio and Ceftriaxone drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Revatio (sildenafil citrate) and Ceftriaxone (ceftriaxone sodium). Common drug interactions include right ventricular failure among females and epistaxis among males.
The phase IV clinical study analyzes what interactions people have when they take Revatio and Ceftriaxone. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.
What is Revatio?
Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.
What is Ceftriaxone?
Ceftriaxone has active ingredients of ceftriaxone sodium. It is often used in typhoid fever. eHealthMe is studying from 40,991 Ceftriaxone users. Check the latest studies of Ceftriaxone.
44 people who take Revatio and Ceftriaxone together, and have interactions are studied.

What are the common drug interactions of Revatio and Ceftriaxone, by gender? *:
female:
- Right ventricular failure (right half of the heart fails to work)
- Dyspnoea (difficult or laboured respiration)
- Fluid retention (an abnormal accumulation of fluid in the blood)
- Hypotension (abnormally low blood pressure)
- Diarrhoea
- Oxygen saturation decreased
- Pyrexia (fever)
- Asthenia (weakness)
- Hospitalisation
- Infection
male:
- Epistaxis (bleed from the nose)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Lacrimation increased
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Productive cough
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Restless legs syndrome (a powerful urge to move your legs)
- Cardiac failure
- Benign prostatic hyperplasia (benign enlargement of the prostate)
- Blood bilirubin increased
What are the common drug interactions of Revatio and Ceftriaxone, by age (0-1 to 60+)? *:
0-1:
- Brain injury
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Respiratory arrest (cessation of normal respiration due to failure of the lungs to function effectively)
- Tracheostomy malfunction (a surgical opening of trachea not working normally)
2-9:
- Pyrexia (fever)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
10-19:
n/a
20-29:
- Device occlusion
30-39:
- Abdominal pain upper
- Application site reaction
- Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)
- Diarrhoea
- Dry skin
- Erythema (redness of the skin)
- Pain in jaw
- Pruritus (severe itching of the skin)
- Rash macular (small, flat red spots)
- Skin disorder (skin disease)
40-49:
- Acute respiratory failure
- Pain
- Pneumonia
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Bronchial hyperreactivity
- Bronchial secretion retention
- Drug hypersensitivity
- Fluid overload (too much fluid in the blood)
- Folliculitis (infection of hair root)
- Hypoxia (low oxygen in tissues)
50-59:
- Productive cough
- Respiratory failure (inadequate gas exchange by the respiratory system)
- Restless legs syndrome (a powerful urge to move your legs)
- Syncope (loss of consciousness with an inability to maintain postural tone)
- Blood bilirubin increased
- Cellulitis (infection under the skin)
- Erythema (redness of the skin)
- Fall
- Peripheral swelling
- Cardiac failure acute
60+:
- Pneumonia
- Epistaxis (bleed from the nose)
- Colon cancer
- Drug eruption (adverse drug reaction of the skin)
- Haemorrhage (bleeding)
- Influenza
- Malaise (a feeling of general discomfort or uneasiness)
- Oxygen saturation decreased
- Platelet count decreased
- Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
What are the existing conditions these people have? *
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 32 people, 72.73%
- Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 5 people, 11.36%
- Right Ventricular Failure (right half of the heart fails to work): 5 people, 11.36%
- Hypokalemia (low potassium): 5 people, 11.36%
- Wheezing (a high-pitched whistling sound made while you breath): 4 people, 9.09%
- Stress And Anxiety: 4 people, 9.09%
- Sedation: 4 people, 9.09%
- Salivary Gland Calculus (stone in salivary gland): 4 people, 9.09%
- Pneumonia: 4 people, 9.09%
- Pain: 4 people, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Revatio and Ceftriaxone?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Revatio (44,849 reports)
- Ceftriaxone (40,991 reports)
Browse all drug interactions of Revatio and Ceftriaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Revatio:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ceftriaxone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Revatio and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ceftriaxone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
- Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
- Agrawal SR, Rajput A, Jain AP, "Leukocytoclastic vasculitis and acute allergic interstitial nephritis following ceftriaxone exposure", Journal of pharmacology & pharmacotherapeutics, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on sildenafil citrate and ceftriaxone sodium (the active ingredients of Revatio and Ceftriaxone, respectively), and Revatio and Ceftriaxone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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