Rezurock and Zofran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rezurock (belumosudil mesylate) and Zofran (ondansetron hydrochloride). Common drug interactions include fatigue among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Rezurock and Zofran. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Rezurock?

Rezurock has active ingredients of belumosudil mesylate. eHealthMe is studying from 1,132 Rezurock users. Check the latest studies of Rezurock.

What is Zofran?

Zofran has active ingredients of ondansetron hydrochloride. It is often used in nausea. eHealthMe is studying from 94,987 Zofran users. Check the latest studies of Zofran.



On Jul, 15, 2026

34 people who take Rezurock and Zofran together, and have interactions are studied.

Rezurock and Zofran drug interactions.

What are the common drug interactions of Rezurock and Zofran, by gender? *:

female:

  1. Fatigue (feeling of tiredness)
  2. Diarrhoea
  3. Headache (pain in head)
  4. Insomnia (sleeplessness)
  5. Pruritus (severe itching of the skin)
  6. Dyspnoea (difficult or laboured respiration)
  7. Rash
  8. Blood creatinine increased
  9. Blood immunoglobulin g decreased
  10. Blood magnesium decreased

male:

  1. Fatigue (feeling of tiredness)
  2. Dry skin
  3. Cough
  4. Erythema (redness of the skin)
  5. Haematocrit decreased
  6. Haemoglobin decreased
  7. Nasopharyngitis (inflammation of the nasopharynx)
  8. Platelet count decreased
  9. Protein total decreased
  10. Red blood cell count decreased

What are the common drug interactions of Rezurock and Zofran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Leukaemia recurrent (repeat cancer of bone marrow or blood cells)

30-39:

  1. Cough
  2. Alanine aminotransferase increased
  3. Aspartate aminotransferase increased
  4. Blood alkaline phosphatase increased
  5. Blood creatinine increased
  6. Blood immunoglobulin g decreased
  7. Blood magnesium decreased
  8. Dyspnoea (difficult or laboured respiration)
  9. Fatigue (feeling of tiredness)
  10. Haematocrit decreased

40-49:

  1. Diarrhoea
  2. Headache (pain in head)

50-59:

  1. Diarrhoea

60+:

  1. Sialoadenitis (inflammation of a salivary gland)
  2. Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
  3. Decreased appetite
  4. Dehydration (dryness resulting from the removal of water)
  5. Drug hypersensitivity
  6. Dysphagia (a condition in which swallowing is difficult or painful)
  7. Epistaxis (bleed from the nose)
  8. Rash
  9. Stomatitis (inflammation of mucous membrane of mouth)
  10. Upper-airway cough syndrome

What are the existing conditions these people have? *

  1. Graft Versus Host Disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body): 13 people, 38.24%
  2. Chronic Graft Versus Host Disease (immune cells attack the host's body cells after transplant): 12 people, 35.29%
  3. Dry Skin: 3 people, 8.82%
  4. Graft Versus Host Disease In Skin (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the skin): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Rezurock and Zofran?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rezurock and Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rezurock:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zofran:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rezurock and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zofran and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on belumosudil mesylate and ondansetron hydrochloride (the active ingredients of Rezurock and Zofran, respectively), and Rezurock and Zofran (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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