Ribasphere and Oxycodone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ribasphere (ribavirin) and Oxycodone (oxycodone hydrochloride). Common drug interactions include pruritus among females and nausea among males.

The phase IV clinical study analyzes what interactions people have when they take Ribasphere and Oxycodone. It is created by eHealthMe based on reports of 95 people who take the same drugs from the FDA, and is updated regularly.

What is Ribasphere?

Ribasphere has active ingredients of ribavirin. It is often used in hepatitis c. eHealthMe is studying from 9,336 Ribasphere users. Check the latest studies of Ribasphere.

What is Oxycodone?

Oxycodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 162,592 Oxycodone users. Check the latest studies of Oxycodone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 19, 2026

95 people who take Ribasphere and Oxycodone together, and have interactions are studied.

Ribasphere and Oxycodone drug interactions.

What are the common drug interactions of Ribasphere and Oxycodone, by gender? *:

female:

  1. Pruritus (severe itching of the skin)
  2. White blood cell count decreased
  3. Pyrexia (fever)
  4. Diarrhoea
  5. Weight decreased
  6. Anaemia (lack of blood)
  7. Hypotension (abnormally low blood pressure)
  8. Irritability
  9. Blood bilirubin increased
  10. Constipation

male:

  1. Nausea (feeling of having an urge to vomit)
  2. Fatigue (feeling of tiredness)
  3. Anxiety
  4. Decreased appetite
  5. Rash
  6. Alopecia (absence of hair from areas of the body)
  7. Pyrexia (fever)
  8. Weight decreased
  9. Arthralgia (joint pain)
  10. Injection site rash

What are the common drug interactions of Ribasphere and Oxycodone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chest pain

40-49:

  1. Asthenia (weakness)
  2. Red blood cell count decreased
  3. Headache (pain in head)
  4. White blood cell count decreased
  5. Pyrexia (fever)
  6. Anaemia (lack of blood)
  7. Abdominal pain
  8. Aspartate aminotransferase increased
  9. Blood bilirubin increased
  10. Constipation

50-59:

  1. Hallucination (an experience involving the perception of something not present)
  2. Hepatitis b
  3. Leukocytosis (increased white blood cells)
  4. Anaphylactic reaction (serious allergic reaction)
  5. Arthralgia (joint pain)
  6. Burning sensation
  7. Depression
  8. Dizziness
  9. Dysphagia (a condition in which swallowing is difficult or painful)
  10. Hypersomnia (excessive daytime sleepiness (eds))

60+:

  1. Fatigue (feeling of tiredness)
  2. Nausea (feeling of having an urge to vomit)
  3. Ammonia increased
  4. Dry skin
  5. Muscle spasms (muscle contraction)
  6. Agitation (state of anxiety or nervous excitement)
  7. Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
  8. Ascites (accumulation of fluid in the abdominal cavity)
  9. Asterixis (flapping tremor, or liver flap)
  10. Diarrhoea

What are the existing conditions these people have? *

  1. High Blood Pressure: 12 people, 12.63%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 5.26%
  3. Depression: 5 people, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Ribasphere and Oxycodone?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ribasphere and Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ribasphere:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Oxycodone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ribasphere and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Oxycodone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ribavirin and oxycodone hydrochloride (the active ingredients of Ribasphere and Oxycodone, respectively), and Ribasphere and Oxycodone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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