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Riboflavin and Methylphenidate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Riboflavin (riboflavin (vitamin b2)) and Methylphenidate (methylphenidate). Common drug interactions include weight decreased among females and pyrexia among males.

The phase IV clinical study analyzes what interactions people have when they take Riboflavin and Methylphenidate. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Riboflavin?

Riboflavin has active ingredients of riboflavin (vitamin b2). It is often used in migraine. eHealthMe is studying from 2,869 Riboflavin users. Check the latest studies of Riboflavin.

What is Methylphenidate?

Methylphenidate has active ingredients of methylphenidate. eHealthMe is studying from 8,216 Methylphenidate users. Check the latest studies of Methylphenidate.

On Jul, 11, 2026

24 people who take Riboflavin and Methylphenidate together, and have interactions are studied.

Riboflavin and Methylphenidate drug interactions.

What are the common drug interactions of Riboflavin and Methylphenidate, by gender? *:

female:

  1. Weight decreased
  2. Dyspnoea (difficult or laboured respiration)
  3. Erythema (redness of the skin)
  4. Head injury
  5. Malaise (a feeling of general discomfort or uneasiness)
  6. Pruritus (severe itching of the skin)
  7. Rash
  8. Dehydration (dryness resulting from the removal of water)
  9. Hypotension (abnormally low blood pressure)
  10. Surgery

male:

  1. Pyrexia (fever)

What are the common drug interactions of Riboflavin and Methylphenidate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Wisdom teeth removal
  2. Bone tuberculosis
  3. Cardiac murmur (an heart sound in valve abnormality)
  4. Diarrhoea
  5. Dizziness
  6. Dyspnoea (difficult or laboured respiration)
  7. Fall
  8. Infusion site hypersensitivity
  9. Nasal discomfort
  10. Nasal inflammation (inflammation of nose)

20-29:

n/a

30-39:

n/a

40-49:

  1. Eye pain
  2. Headache (pain in head)
  3. Nausea (feeling of having an urge to vomit)

50-59:

  1. Cough
  2. Dyspnoea (difficult or laboured respiration)
  3. Wheezing (a high-pitched whistling sound made while you breath)

60+:

n/a

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 58.33%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 11 people, 45.83%
  3. Immunodeficiency Common Variable: 6 people, 25.00%
  4. Asthma: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Riboflavin and Methylphenidate?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Riboflavin and Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Riboflavin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Methylphenidate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Riboflavin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Methylphenidate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on riboflavin (vitamin b2) and methylphenidate (the active ingredients of Riboflavin and Methylphenidate, respectively), and Riboflavin and Methylphenidate (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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