Risperdal and Mucinex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperdal (risperidone) and Mucinex (guaifenesin). Common drug interactions include binge eating among females and headache among males.

The phase IV clinical study analyzes what interactions people have when they take Risperdal and Mucinex. It is created by eHealthMe based on reports of 52 people who take the same drugs from the FDA, and is updated regularly.

What is Risperdal?

Risperdal has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 127,729 Risperdal users. Check the latest studies of Risperdal.

What is Mucinex?

Mucinex has active ingredients of guaifenesin. It is often used in cough. eHealthMe is studying from 29,749 Mucinex users. Check the latest studies of Mucinex.



On Jul, 27, 2026

52 people who take Risperdal and Mucinex together, and have interactions are studied.

Risperdal and Mucinex drug interactions.

What are the common drug interactions of Risperdal and Mucinex, by gender? *:

female:

  1. Binge eating (pattern of disordered eating which consists of episodes of uncontrollable eating)
  2. Mania (a state of abnormally elevated or irritable mood)
  3. Psychotic disorder
  4. Weight decreased
  5. Drug ineffective
  6. Therapeutic response unexpected
  7. Anxiety
  8. Pain in extremity
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  10. Hypertension (high blood pressure)

male:

  1. Headache (pain in head)
  2. Chest pain
  3. Pyrexia (fever)
  4. Sinusitis (inflammation of sinus)
  5. Abdominal pain upper
  6. Abscess (pus)
  7. Allodynia (a condition in which pain is caused by a stimulus that does not normally elicit pain)
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Ankle fracture
  10. Anxiety

What are the common drug interactions of Risperdal and Mucinex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Aggression
  2. Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)

20-29:

  1. Diabetes mellitus inadequate control
  2. Gestational diabetes (diabetes in pregnancy)
  3. Hyperglycaemia (high blood sugar)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Type 1 diabetes mellitus
  6. Type 2 diabetes mellitus
  7. Weight increased
  8. Abdominal discomfort
  9. Anxiety
  10. Depression

30-39:

  1. Brain injury
  2. Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
  3. Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
  4. Sepsis (a severe blood infection that can lead to organ failure and death)

40-49:

  1. Infection
  2. Neuropathy peripheral (surface nerve damage)
  3. Renal failure (kidney dysfunction)
  4. Type 2 diabetes mellitus
  5. Abdominal pain
  6. Arthralgia (joint pain)
  7. Asthma
  8. Autoimmune hepatitis
  9. Blood cholesterol increased
  10. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

50-59:

  1. Anxiety
  2. Aortic arteriosclerosis (hardening of the aortic arteries)
  3. Atelectasis (partial or complete collapse of the lung)
  4. Blood urea nitrogen/creatinine ratio increased
  5. Bronchopleural fistula
  6. Bunion (a painful swelling on the first joint of the big toe)
  7. Cancer pain
  8. Cardiomegaly (increased size of heart than normal)
  9. Cerebrovascular disorder (disease of brain)
  10. Cervical spinal stenosis (narrowing of the spinal canal in the neck)

60+:

  1. Anaemia (lack of blood)
  2. Anxiety
  3. Femur fracture
  4. Gastritis (inflammation of stomach)
  5. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
  6. Joint dislocation (a joint position is changed from normal position)
  7. Kyphosis (a condition of over-curvature of the thoracic vertebrae (upper back))
  8. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  9. Muscular weakness (muscle weakness)
  10. Osteoporosis (bones weak and more likely to break)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 19 people, 36.54%
  2. Depression: 5 people, 9.62%
  3. Pain: 4 people, 7.69%
  4. Immunodeficiency Common Variable: 4 people, 7.69%
  5. Stress And Anxiety: 3 people, 5.77%
  6. Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 5.77%
  7. Major Depression (a mood state that goes well beyond temporarily feeling sad or blue. it is a serious medical illness that affects one's thoughts, feelings): 3 people, 5.77%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 5.77%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Risperdal and Mucinex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Risperdal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Mucinex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Risperdal and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Mucinex and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on risperidone and guaifenesin (the active ingredients of Risperdal and Mucinex, respectively), and Risperdal and Mucinex (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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