Risperidone and Ampyra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Risperidone (risperidone) and Ampyra (dalfampridine). Common drug interactions include tongue blistering among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Risperidone and Ampyra. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.

What is Risperidone?

Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.

What is Ampyra?

Ampyra has active ingredients of dalfampridine. It is often used in multiple sclerosis. eHealthMe is studying from 77,145 Ampyra users. Check the latest studies of Ampyra.

On Jul, 26, 2026

91 people who take Risperidone and Ampyra together, and have interactions are studied.

Risperidone and Ampyra drug interactions.

What are the common drug interactions of Risperidone and Ampyra, by gender? *:

female:

Tongue blistering
Vomiting
Asthenia (weakness)
Diarrhoea
Eye disorder
Gastric dilatation (a twisted stomach)
Hepatic enzyme increased
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development)
Type 2 diabetes mellitus
Vertigo

male:

Fall
Mobility decreased (ability to move is reduced)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Headache (pain in head)
Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Eye movement disorder
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Dizziness
Dysstasia (difficulty in standing)

What are the common drug interactions of Risperidone and Ampyra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Abdominal discomfort
Flushing (the warm, red condition of human skin)
Hepatic enzyme increased

30-39:

Mobility decreased (ability to move is reduced)
Arthralgia (joint pain)
Contusion (a type of hematoma of tissue in which capillaries)
Fall
Fatigue (feeling of tiredness)
Limb discomfort (discomfort in leg)
Joint injury
Gait disturbance
Balance disorder
Muscular weakness (muscle weakness)

40-49:

Balance disorder
Fatigue (feeling of tiredness)
Ligament sprain (ligament stretched)
Memory impairment
Onychomycosis (fungal infection of the nail)
Thermohypoaesthesia (a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli heat)
Arthralgia (joint pain)
Blood sodium decreased
Confusional state
Dysarthria (speech disorder)

50-59:

Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Weight increased
Urinary tract infection
Memory impairment
Fall
Fatigue (feeling of tiredness)
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Dizziness
Abasia (inability to walk)
Intervertebral disc protrusion (spinal disc protrusion)

60+:

Back pain
Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Muscular weakness (muscle weakness)
Muscle spasms (muscle contraction)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Gait disturbance
Respiratory failure (inadequate gas exchange by the respiratory system)
Seizure (abnormal excessive or synchronous neuronal activity in the brain)
Hepatic enzyme increased
Nasopharyngitis (inflammation of the nasopharynx)

What are the existing conditions these people have? *

Gait Disturbance: 27 people, 29.67%

* Approximation only. Some reports may have incomplete information.

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