Risperidone and Librium drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Risperidone (risperidone) and Librium (chlordiazepoxide hydrochloride). Common drug interactions include drug abuse among females and anhedonia among males.
The phase IV clinical study analyzes what interactions people have when they take Risperidone and Librium. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Risperidone?
Risperidone has active ingredients of risperidone. It is often used in bipolar disorder. eHealthMe is studying from 72,175 Risperidone users. Check the latest studies of Risperidone.
What is Librium?
Librium has active ingredients of chlordiazepoxide hydrochloride. It is often used in stress and anxiety. eHealthMe is studying from 2,490 Librium users. Check the latest studies of Librium.
18 people who take Risperidone and Librium together, and have interactions are studied.

What are the common drug interactions of Risperidone and Librium, by gender? *:
female:
- Drug abuse
- Sopor (sleep)
- Blood glucose increased
- Colitis (inflammation of colon)
- Dehydration (dryness resulting from the removal of water)
- Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
- Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Renal failure acute (rapid kidney dysfunction)
- Ulcer
male:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Chronic kidney disease
- Blood creatine phosphokinase increased
- Confusional state
- Delirium tremens (a psychotic condition typical of withdrawal in chronic alcoholics)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Drug toxicity
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Hallucination, visual (seeing things that aren't there)
- Hyperhidrosis (abnormally increased sweating)
What are the common drug interactions of Risperidone and Librium, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Blood creatine phosphokinase increased
- Hyperhidrosis (abnormally increased sweating)
- Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
- Pyrexia (fever)
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Tremor (trembling or shaking movements in one or more parts of your body)
- Upper respiratory tract infection
30-39:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Chronic kidney disease
- Emotional distress
- Pain
- Renal failure (kidney dysfunction)
- Lethargy (tiredness)
- Partner stress
- Anticonvulsant drug level increased
- Drug level increased
- Drug toxicity
40-49:
- Sopor (sleep)
- Alcohol poisoning
- Alcohol withdrawal syndrome
- Confusional state
- Delirium tremens (a psychotic condition typical of withdrawal in chronic alcoholics)
- Disorientation (disability in which the senses of time, direction, and recognition of people and places)
- Hallucination, auditory (perceiving sounds without auditory stimulus)
- Hallucination, visual (seeing things that aren't there)
- Hypoventilation (too shallow or too slow breathing, which does not meet the needs of the body)
- Intentional self-injury
50-59:
n/a
60+:
- Blood glucose increased
- Colitis (inflammation of colon)
- Dehydration (dryness resulting from the removal of water)
- Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
- Helicobacter infection (helicobacter pylori (h. pylori) infects stomach)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Renal failure acute (rapid kidney dysfunction)
- Ulcer
- Vomiting
What are the existing conditions these people have? *
- Hiv Infection: 3 people, 16.67%
- Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 2 people, 11.11%
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 5.56%
- Psoriasis (immune-mediated disease that affects the skin): 1 person, 5.56%
- High Blood Cholesterol: 1 person, 5.56%
- Extrapyramidal Disorder (involuntary muscle spasms in the face and neck): 1 person, 5.56%
- Diabetes: 1 person, 5.56%
- Delirium Tremens (a psychotic condition typical of withdrawal in chronic alcoholics): 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Risperidone and Librium?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Risperidone (72,175 reports)
- Librium (2,490 reports)
Browse all drug interactions of Risperidone and Librium:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Risperidone:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Librium:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Risperidone and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Librium and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
- Janardhana P, Nagaraj AK, Basavanna PL, "Risperidone-induced skin rash", Indian journal of psychiatry, 2016 Jan .
- Dsouza MC, "Could risperidone have caused the cataract?: A case report and review of literature", Journal of Research in Psychiatry and Behavioral Science, 2015 Jan .
- Dsouza MC, "COULD RISPERIDONE HAVE CAUSED THE CATARACT", JRPBS, 2015 Jan .
- Ray RK, Bashir MA, Rao S, "Co-Administration of Risperidone and Sodium Valproate Causing Bilateral Chronic Exertional Lower Leg Compartment Syndrome", Open Journal of Orthopedics, 2014 Apr .
- Hosseini, S. H., & Ahmadi, A., "Peripheral edema occurring during treatment with risperidone combined with citalopram", Case reports in medicine, 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on risperidone and chlordiazepoxide hydrochloride (the active ingredients of Risperidone and Librium, respectively), and Risperidone and Librium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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