Ritalin and Arthrotec drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ritalin (methylphenidate hydrochloride) and Arthrotec (diclofenac sodium; misoprostol). Common drug interactions include gait disturbance among females and cerebrovascular accident among males.

The phase IV clinical study analyzes what interactions people have when they take Ritalin and Arthrotec. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Arthrotec?

Arthrotec has active ingredients of diclofenac sodium; misoprostol. It is often used in arthritis. eHealthMe is studying from 11,986 Arthrotec users. Check the latest studies of Arthrotec.

On Aug, 11, 2026

28 people who take Ritalin and Arthrotec together, and have interactions are studied.

Ritalin and Arthrotec drug interactions.

What are the common drug interactions of Ritalin and Arthrotec, by gender? *:

female:

Gait disturbance
Glossodynia (a burning or painful sensation in the tongue)
Heart rate increased
Hyperaesthesia
Injection site reaction
Plantar fasciitis (painful inflammatory process of the plantar fascia)
Tongue disorder (disease of tongue)
Abdominal pain upper
Affect lability (emotional incontinence)
Anaemia (lack of blood)

male:

Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Blood pressure increased
Asthenia (weakness)
Blood pressure fluctuation
Cataract (clouding of the lens inside the eye)
Colitis microscopic (inflammation of colon with diarrhoea and abdominal cramps)
Coma (state of unconsciousness lasting more than six hours)
Crying
Decreased appetite
Depressed mood

What are the common drug interactions of Ritalin and Arthrotec, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Gait disturbance
Heart rate increased
Hyperaesthesia
Hypoaesthesia (reduced sense of touch or sensation)
Injection site reaction
Muscle spasms (muscle contraction)
Nausea (feeling of having an urge to vomit)

30-39:

n/a

40-49:

Influenza
Insomnia (sleeplessness)
Irritability
Leukopenia (less number of white blood cells in blood)
Memory impairment
Muscle twitching
Myalgia (muscle pain)
Rash
Headache (pain in head)
Somnolence (a state of near-sleep, a strong desire for sleep)

50-59:

Diarrhoea
Exostosis (formation of new bone on the surface of a bone)
Foot deformity (functional disability of foot)
Headache (pain in head)
Plantar fasciitis (painful inflammatory process of the plantar fascia)
Somnolence (a state of near-sleep, a strong desire for sleep)
Hip arthroplasty
Protein s deficiency
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)

60+:

Glossodynia (a burning or painful sensation in the tongue)
Tongue disorder (disease of tongue)
Chest discomfort
Coombs negative haemolytic anaemia
Cytomegalovirus test positive
Dizziness
Haemolytic anaemia (anaemia due to haemolysis)
Rash
Serum ferritin increased

What are the existing conditions these people have? *

Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 9 people, 32.14%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 9 people, 32.14%
Insomnia (sleeplessness): 8 people, 28.57%
Cervical Spinal Stenosis (narrowing of the spinal canal in the neck): 8 people, 28.57%
Acne (skin problems that cause pimples): 8 people, 28.57%
Pain: 3 people, 10.71%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 7.14%
Migraine (headache): 2 people, 7.14%

* Approximation only. Some reports may have incomplete information.

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