Ritalin and Cataflam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ritalin (methylphenidate hydrochloride) and Cataflam (diclofenac potassium). Common drug interactions include hypoaesthesia among females and feeling drunk among males.

The phase IV clinical study analyzes what interactions people have when they take Ritalin and Cataflam. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Cataflam?

Cataflam has active ingredients of diclofenac potassium. It is often used in pain. eHealthMe is studying from 1,851 Cataflam users. Check the latest studies of Cataflam.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

15 people who take Ritalin and Cataflam together, and have interactions are studied.

What are the common drug interactions of Ritalin and Cataflam, by gender? *:

female:

Hypoaesthesia (reduced sense of touch or sensation)
Epistaxis (bleed from the nose)
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Weight increased
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
Bipolar disorder (mood disorder)
Blood cholesterol increased
Blood iron decreased

male:

Feeling drunk
Acute myocardial infarction (acute heart attack)
Therapeutic response unexpected
Weight decreased
Chest pain
Depressed level of consciousness
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hallucination (an experience involving the perception of something not present)
Nausea (feeling of having an urge to vomit)

What are the common drug interactions of Ritalin and Cataflam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Feeling drunk
Depressed level of consciousness
Hallucination (an experience involving the perception of something not present)
Nightmare (unpleasant dream)

30-39:

Epistaxis (bleed from the nose)
Hypoaesthesia (reduced sense of touch or sensation)
Nausea (feeling of having an urge to vomit)
Facial paresis (weakness in facial muscle movement)
Aphasia (damage to the parts of the brain that control language)
Blood chloride increased
Carbon dioxide decreased
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Dysphagia (a condition in which swallowing is difficult or painful)
Emotional disorder

40-49:

Feeling drunk
Therapeutic response unexpected
Weight decreased

50-59:

Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hypersensitivity
Hypoaesthesia (reduced sense of touch or sensation)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Peripheral swelling
Sensitivity of teeth
Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)

60+:

n/a

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 5 people, 33.33%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 5 people, 33.33%
Restless Leg Syndrome (a powerful urge to move your legs): 3 people, 20.00%
Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 2 people, 13.33%
Musculoskeletal Discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 2 people, 13.33%
Glaucoma (increased fluid pressure in the eye with vision loss): 1 person, 6.67%
Bladder Disorder: 1 person, 6.67%
Depression: 1 person, 6.67%
Drowsiness: 1 person, 6.67%
Gait Disturbance: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

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