1. Home
  2. Analysis
  3. Ritalin
  4. Extavia

Ritalin and Extavia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ritalin (methylphenidate hydrochloride) and Extavia (interferon beta-1b). Common drug interactions include pyrexia among females and panic reaction among males.

The phase IV clinical study analyzes what interactions people have when they take Ritalin and Extavia. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Extavia?

Extavia has active ingredients of interferon beta-1b. It is often used in multiple sclerosis. eHealthMe is studying from 4,888 Extavia users. Check the latest studies of Extavia.

On Jul, 19, 2026

13 people who take Ritalin and Extavia together, and have interactions are studied.

Ritalin and Extavia drug interactions.

What are the common drug interactions of Ritalin and Extavia, by gender? *:

female:

  1. Pyrexia (fever)
  2. Temperature intolerance (inability to go in temperature)
  3. Weight increased
  4. Influenza
  5. Fatigue (feeling of tiredness)
  6. Injection site reaction
  7. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  8. Rash pruritic (redness with itching)
  9. Vitamin b12 decreased
  10. Erythema (redness of the skin)

male:

  1. Panic reaction

What are the common drug interactions of Ritalin and Extavia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Panic reaction

30-39:

  1. Fatigue (feeling of tiredness)
  2. Injection site reaction
  3. Vitamin b12 decreased
  4. Influenza
  5. Pain in extremity
  6. Pyrexia (fever)
  7. Sinus disorder (disease of sinus)
  8. Sneezing
  9. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)
  10. Diplopia (double vision)

40-49:

n/a

50-59:

  1. Chills (felling of cold)
  2. Eye irritation
  3. Weight increased
  4. Rash pruritic (redness with itching)
  5. Erythema (redness of the skin)
  6. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
  7. Vitreous floaters (spots before the eyes)
  8. Diarrhoea
  9. Influenza
  10. Nausea (feeling of having an urge to vomit)

60+:

n/a

What are the existing conditions these people have? *

  1. Diabetes: 5 people, 38.46%
  2. Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Ritalin and Extavia?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Ritalin and Extavia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ritalin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Extavia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ritalin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Extavia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies

How the study uses the data?

The study uses data from the FDA. It is based on methylphenidate hydrochloride and interferon beta-1b (the active ingredients of Ritalin and Extavia, respectively), and Ritalin and Extavia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.