Ritalin and Opdivo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ritalin (methylphenidate hydrochloride) and Opdivo (nivolumab). Common drug interactions include death among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Ritalin and Opdivo. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Opdivo?

Opdivo has active ingredients of nivolumab. eHealthMe is studying from 56,331 Opdivo users. Check the latest studies of Opdivo.

On Jul, 18, 2026

33 people who take Ritalin and Opdivo together, and have interactions are studied.

What are the common drug interactions of Ritalin and Opdivo, by gender? *:

female:

Death
Diarrhoea
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Abdominal pain
Arthralgia (joint pain)
Blood sodium decreased
Dyspnoea (difficult or laboured respiration)
Joint swelling
Muscle disorder (muscle disease)

male:

Fatigue (feeling of tiredness)
Blood pressure fluctuation
Vomiting
Asthenia (weakness)
Constipation
Muscular weakness (muscle weakness)
Abdominal distension
Adrenal disorder
Chest discomfort
Dry mouth

What are the common drug interactions of Ritalin and Opdivo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Malignant neoplasm progression (cancer tumour came back)
Rash
Tooth infection

50-59:

Death

60+:

Diarrhoea
Blood pressure fluctuation
Dysphonia (speech disorder attributable to a disorder of phonation)
Exostosis (formation of new bone on the surface of a bone)
Glossodynia (a burning or painful sensation in the tongue)
Hypogeusia (reduced ability to taste things (to taste sweet, sour, bitter, or salty substances))
Nausea (feeling of having an urge to vomit)
Oral pain
Pulmonary embolism (blockage of the main artery of the lung)
Rash

What are the existing conditions these people have? *

Renal Cell Carcinoma Stage Iv (stage iv renal cell cancer have cancer that has spread to other organs, such as the lungs, liver, bones, or brain, and may have spread to lymph nodes): 5 people, 15.15%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 4 people, 12.12%
Glioblastoma (most common and most aggressive malignant primary brain tumour in humans): 4 people, 12.12%
Retroperitoneal Cancer (cancer between the peritoneum and the posterior abdominal wall): 2 people, 6.06%
Pancreatic Carcinoma (pancreatic cancer): 2 people, 6.06%
Pain: 2 people, 6.06%
Nausea (feeling of having an urge to vomit): 2 people, 6.06%
Lung Neoplasm Malignant (cancer tumour of lung): 2 people, 6.06%
Lung Cancer Metastatic (lung cancer spreads to other parts): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

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