Ritalin and Propulsid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ritalin (methylphenidate hydrochloride) and Propulsid (cisapride monohydrate). Common drug interactions include anasarca among females and nervousness among males.

The phase IV clinical study analyzes what interactions people have when they take Ritalin and Propulsid. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Propulsid?

Propulsid has active ingredients of cisapride monohydrate. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 8,130 Propulsid users. Check the latest studies of Propulsid.

On Jul, 08, 2026

21 people who take Ritalin and Propulsid together, and have interactions are studied.

Ritalin and Propulsid drug interactions.

What are the common drug interactions of Ritalin and Propulsid, by gender? *:

female:

Anasarca (general swelling, or massive oedema)
Arrhythmia (irregular heartbeat)
Blood in stool
Blood potassium decreased
Candidal infection (fungal infection)
Cardiac disorder
Cardiomyopathy (weakening of the heart muscle)
Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
Cholestasis (a condition where bile cannot flow from the liver to the duodenum)

male:

Nervousness
Oesophageal disorder (disease of oesophagus)
Muscle weakness (a lack of muscle strength)
Myalgia (muscle pain)
Oedema (fluid collection in tissue)
Pain
Pain in limb
Peripheral neuropathy (damage to nerves of the peripheral nervous system)
Pneumonia
Sedation

What are the common drug interactions of Ritalin and Propulsid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Oesophageal disorder (disease of oesophagus)

10-19:

Arthralgia (joint pain)
Difficulty in walking
Weakness

20-29:

Post procedural complication
Procedural pain
Spinal fracture (fracture in one of vertebrae)

30-39:

Dependence
Suicidal ideation

40-49:

Joint dislocation (a joint position is changed from normal position)
Ketonuria (ketones in urine)
Lethargy (tiredness)
Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
Lung neoplasm (tumour of lung)
Lymphadenopathy (disease or enlargement of lymph nodes)
Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
Memory impairment
Mitral valve prolapse (heart's mitral valve doesn't work well)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)

50-59:

Coma (state of unconsciousness lasting more than six hours)
Confusion
Localised exfoliation (a peeling off or loss of epidermis at the site of exposure)
Renal failure (kidney dysfunction)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Sweating increased (excess sweating)
Weakness

60+:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Asthenia (weakness)
Oedema (fluid collection in tissue)
Pain
Pain in limb
Peripheral neuropathy (damage to nerves of the peripheral nervous system)
Pneumonia
Sedation
Stomatitis (inflammation of mucous membrane of mouth)
Tinnitus (a ringing in the ears)

What are the existing conditions these people have? *

Pain: 3 people, 14.29%
Stress And Anxiety: 2 people, 9.52%
Seasonal Allergy (allergic condition due to certain season): 2 people, 9.52%
Salivary Hypersecretion (excess saliva secretion): 2 people, 9.52%
Muscle Spasms (muscle contraction): 2 people, 9.52%
Migraine (headache): 2 people, 9.52%
Micturition Urgency (urgency to pass the urine): 2 people, 9.52%
Insomnia (sleeplessness): 2 people, 9.52%
Ill-Defined Disorder: 2 people, 9.52%
Headache (pain in head): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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