Ritalin and Revatio drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Ritalin (methylphenidate hydrochloride) and Revatio (sildenafil citrate). Common drug interactions include dyspnoea among females and neuralgia among males.

The phase IV clinical study analyzes what interactions people have when they take Ritalin and Revatio. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Ritalin?

Ritalin has active ingredients of methylphenidate hydrochloride. It is often used in attention deficit hyperactivity disorder. eHealthMe is studying from 29,427 Ritalin users. Check the latest studies of Ritalin.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.

On Jul, 20, 2026

24 people who take Ritalin and Revatio together, and have interactions are studied.

What are the common drug interactions of Ritalin and Revatio, by gender? *:

female:

Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Leukopenia (less number of white blood cells in blood)
Migraine (headache)
Oedema peripheral (superficial swelling)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)

male:

Neuralgia (pain in one or more nerves)
Somnolence (a state of near-sleep, a strong desire for sleep)
Empyema (collection of pus in a cavity in the body)
Pericardial effusion (fluid around the heart)
Postoperative wound infection
Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Injury
Muscle spasms (muscle contraction)

What are the common drug interactions of Ritalin and Revatio, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Back pain
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chronic kidney disease
Muscle spasms (muscle contraction)
Muscle tightness
Nasopharyngitis (inflammation of the nasopharynx)
Tremor (trembling or shaking movements in one or more parts of your body)

50-59:

Food craving
Insomnia (sleeplessness)
Weight increased
Drug ineffective
Fatigue (feeling of tiredness)

60+:

Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Failure to thrive (inadequate weight gain and physical growth in children)
Leukopenia (less number of white blood cells in blood)
Migraine (headache)
Oedema peripheral (superficial swelling)
Pain in extremity
Palpitations (feelings or sensations that your heart is pounding or racing)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 11 people, 45.83%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 29.17%
Neuralgia (pain in one or more nerves): 4 people, 16.67%
Pain: 3 people, 12.50%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 12.50%
Depression: 3 people, 12.50%
Wheezing (a high-pitched whistling sound made while you breath): 2 people, 8.33%
Osteoarthritis (a joint disease caused by cartilage loss in a joint): 2 people, 8.33%
Oedema (fluid collection in tissue): 2 people, 8.33%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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