Rivaroxaban and Gemfibrozil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rivaroxaban (rivaroxaban) and Gemfibrozil (gemfibrozil). Common drug interactions include left ventricular failure among females and gastrointestinal haemorrhage among males.

The phase IV clinical study analyzes what interactions people have when they take Rivaroxaban and Gemfibrozil. It is created by eHealthMe based on reports of 26 people who take the same drugs from the FDA, and is updated regularly.

What is Rivaroxaban?

Rivaroxaban has active ingredients of rivaroxaban. It is often used in blood clots. eHealthMe is studying from 26,544 Rivaroxaban users. Check the latest studies of Rivaroxaban.

What is Gemfibrozil?

Gemfibrozil has active ingredients of gemfibrozil. It is often used in high blood cholesterol. eHealthMe is studying from 18,213 Gemfibrozil users. Check the latest studies of Gemfibrozil.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 19, 2026

26 people who take Rivaroxaban and Gemfibrozil together, and have interactions are studied.

Rivaroxaban and Gemfibrozil drug interactions.

What are the common drug interactions of Rivaroxaban and Gemfibrozil, by gender? *:

female:

Left ventricular failure (left ventricle fails to contract forcefully)
Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal pain upper
Asthenia (weakness)
Death
Faeces discoloured
Fall
Fatigue (feeling of tiredness)
Femur fracture
Myopathy (a muscular disease in which the muscle fibres do not function)

male:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Aneurysm (enlargement of an artery caused by a weakening of the artery wall)
Diarrhoea
Diarrhoea haemorrhagic (bloody diarrhoea)
Diarrhoea infectious (bacteria, viruses, and other germs can cause diarrhoea)
Drug level increased
Aortic valve sclerosis (narrowing of the aortic valve)
Atrial tachycardia (rhythm disturbance that arises in the atria)
Back pain
Cardiac disorder

What are the common drug interactions of Rivaroxaban and Gemfibrozil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Splenomegaly (enlargement of spleen)

50-59:

Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Dyspnoea (difficult or laboured respiration)
Left ventricular dysfunction
Mitral valve incompetence (inefficient heart valve)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Tricuspid valve incompetence (inefficient heart valve)
Anal haemorrhage
Ankle fracture
Dehydration (dryness resulting from the removal of water)
Diarrhoea

60+:

Left ventricular failure (left ventricle fails to contract forcefully)
Respiratory failure (inadequate gas exchange by the respiratory system)
Death
Faeces discoloured
Fall
Fatigue (feeling of tiredness)
Femur fracture
Hyperbilirubinaemia (excess of bilirubin in the blood)
Joint effusion (presence of extra fluid in joint covering)
Myopathy (a muscular disease in which the muscle fibres do not function)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 7 people, 26.92%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 15.38%
Prostate Cancer: 3 people, 11.54%
High Blood Pressure: 3 people, 11.54%
Dyslipidaemia (abnormal amount of lipids): 3 people, 11.54%
Glucose Tolerance Impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis): 2 people, 7.69%
Erdheim-Chester Disease (abnormal multiplication of a specific type of white blood cells): 2 people, 7.69%
Ankle Fracture: 2 people, 7.69%

* Approximation only. Some reports may have incomplete information.

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