Rivaroxaban and Levaquin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rivaroxaban (rivaroxaban) and Levaquin (levofloxacin). Common drug interactions include renal failure among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Rivaroxaban and Levaquin. It is created by eHealthMe based on reports of 44 people who take the same drugs from the FDA, and is updated regularly.

What is Rivaroxaban?

Rivaroxaban has active ingredients of rivaroxaban. It is often used in blood clots. eHealthMe is studying from 26,544 Rivaroxaban users. Check the latest studies of Rivaroxaban.

What is Levaquin?

Levaquin has active ingredients of levofloxacin. It is often used in sinusitis. eHealthMe is studying from 56,638 Levaquin users. Check the latest studies of Levaquin.

On Aug, 02, 2026

44 people who take Rivaroxaban and Levaquin together, and have interactions are studied.

Rivaroxaban and Levaquin drug interactions.

What are the common drug interactions of Rivaroxaban and Levaquin, by gender? *:

female:

Renal failure (kidney dysfunction)
Chronic kidney disease
Confusional state
Hepatic failure (liver failure)
Neoplasm progression (growth of tumour)
Renal injury (kidney injury)
Anaemia (lack of blood)
Large intestine perforation (hole in large intestine)
Pelvic abscess
Peritonitis (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Cardiac failure
Dyspnoea (difficult or laboured respiration)
Ear pain
Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
Influenza like illness
Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
Nasal congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels)
Pain in jaw
Sputum increased

What are the common drug interactions of Rivaroxaban and Levaquin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Abdominal discomfort
Abdominal pain
Dehydration (dryness resulting from the removal of water)
Epistaxis (bleed from the nose)
Haematuria (presence of blood in urine)
Haemoglobin decreased
Myasthenic syndrome (a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion)
Pelvic venous thrombosis (blood clot occurring inside a blood vessel and thromboses (dvts) that form in the deep veins of the legs or in the pelvic veins)
Pulmonary alveolar haemorrhage (acute bleeding)
Pulmonary embolism (blockage of the main artery of the lung)

40-49:

Renal failure (kidney dysfunction)
Chronic kidney disease

50-59:

Confusional state
Hepatic failure (liver failure)
Neoplasm progression (growth of tumour)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Pyrexia (fever)

60+:

Arthralgia (joint pain)
Chest discomfort
Pyrexia (fever)
Sputum increased
Vitamin a deficiency
Wheezing (a high-pitched whistling sound made while you breath)
Sepsis (a severe blood infection that can lead to organ failure and death)
Influenza like illness
Cardiac failure
Bronchiectasis (abnormal widening of the bronchi or their branches, causing a risk of infection)

What are the existing conditions these people have? *

High Blood Pressure: 21 people, 47.73%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 36.36%
Pneumonia: 12 people, 27.27%
Pain: 10 people, 22.73%
Insomnia (sleeplessness): 9 people, 20.45%
Constipation: 9 people, 20.45%
Cough: 8 people, 18.18%
Cystic Fibrosis (disease of the secretary glands): 8 people, 18.18%
Dyspnea (difficult or laboured breathing): 8 people, 18.18%
Stress And Anxiety: 8 people, 18.18%

* Approximation only. Some reports may have incomplete information.

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