Rizatriptan benzoate and Spironolactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rizatriptan benzoate (rizatriptan benzoate) and Spironolactone (spironolactone). Common drug interactions include abdominal pain upper among females and hypoaesthesia among males.

The phase IV clinical study analyzes what interactions people have when they take Rizatriptan benzoate and Spironolactone. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.

What is Rizatriptan benzoate?

Rizatriptan benzoate has active ingredients of rizatriptan benzoate. It is often used in migraine. eHealthMe is studying from 1,886 Rizatriptan benzoate users. Check the latest studies of Rizatriptan benzoate.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

On Jul, 05, 2026

12 people who take Rizatriptan benzoate and Spironolactone together, and have interactions are studied.

Rizatriptan benzoate and Spironolactone drug interactions.

What are the common drug interactions of Rizatriptan Benzoate and Spironolactone, by gender? *:

female:

Abdominal pain upper
Back pain
Breast abscess
Cough
Electrocardiogram qt prolonged
Fall
Fatigue (feeling of tiredness)
Impaired healing
Lower respiratory tract infection
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)

male:

Hypoaesthesia (reduced sense of touch or sensation)
Gait disturbance
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Neuropathy peripheral (surface nerve damage)
Intervertebral disc protrusion (spinal disc protrusion)
Aortic dilatation
Arthropathy
Back pain
Eye disorder
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)

What are the common drug interactions of Rizatriptan Benzoate and Spironolactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Cardiac failure
Congestive cardiomyopathy (weakening of heart muscle)
Left ventricular dysfunction
Sleep disorder
Tachycardia (a heart rate that exceeds the range of 100 beats/min)

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Impaired healing
Lower respiratory tract infection
Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
Nasopharyngitis (inflammation of the nasopharynx)
Nausea (feeling of having an urge to vomit)
Neck pain
Oropharyngeal pain
Pain
Pneumonia

60+:

Drug ineffective
Influenza
Malignant neoplasm progression (cancer tumour came back)
Respiratory failure (inadequate gas exchange by the respiratory system)

What are the existing conditions these people have? *

Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 25.00%
Depression: 3 people, 25.00%
Medullary Thyroid Cancer (type of thyroid cancer that develops in the parafollicular cells of the thyroid gland): 3 people, 25.00%
Pneumonia: 3 people, 25.00%
Mental Disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability): 3 people, 25.00%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 16.67%
High Blood Cholesterol: 2 people, 16.67%
Impaired Gastric Emptying: 2 people, 16.67%
Meniere's Disease (a disorder of the inner ear that can affect hearing and balance to a varying degree): 2 people, 16.67%
Cardiac Disorder: 2 people, 16.67%

* Approximation only. Some reports may have incomplete information.

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