Robaxin and Divalproex drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robaxin (methocarbamol) and Divalproex (divalproex sodium). Common drug interactions include arthralgia among females and astigmatism among males.

The phase IV clinical study analyzes what interactions people have when they take Robaxin and Divalproex. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

What is Divalproex?

Divalproex has active ingredients of divalproex sodium. It is often used in bipolar disorder. eHealthMe is studying from 14,063 Divalproex users. Check the latest studies of Divalproex.

On Aug, 05, 2026

21 people who take Robaxin and Divalproex together, and have interactions are studied.

Robaxin and Divalproex drug interactions.

What are the common drug interactions of Robaxin and Divalproex, by gender? *:

female:

Arthralgia (joint pain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Cough
Fall
Fatigue (feeling of tiredness)
Pneumonia
Spinal disorder (disease of spine a back bone)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Cardiac disorder
Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens)

male:

Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Pilonidal cyst
Presbyopia (a condition in which the lens of the eye loses its ability to focus, making it difficult to see objects up close)
Radiculopathy (a set of conditions in which one or more nerves is affected and does not work properly)
Schizoaffective disorder (a mental disorder characterized by disordered thought)
Subcutaneous abscess
Suicidal ideation
Tardive dyskinesia (a disorder that involves involuntary movements)

What are the common drug interactions of Robaxin and Divalproex, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Chronic kidney disease
Renal failure (kidney dysfunction)
Renal injury (kidney injury)

30-39:

n/a

40-49:

Drug ineffective
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Cyst (a closed sac)
Depression
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Diabetic retinopathy (damage to the retina caused by complications of diabetes)
Drug abuse
Hallucination, visual (seeing things that aren't there)

50-59:

Activities of daily living impaired
Dehydration (dryness resulting from the removal of water)
Diarrhoea
Hyperhidrosis (abnormally increased sweating)
Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
Anxiety
Chronic kidney disease
Dyspnoea (difficult or laboured respiration)
Renal failure (kidney dysfunction)

60+:

Arthralgia (joint pain)
Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
Immune system disorder
Infection
Infusion site discomfort
Infusion site swelling
Pain
Sinusitis (inflammation of sinus)
Swelling
Syncope (loss of consciousness with an inability to maintain postural tone)

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 10 people, 47.62%
Hypergammaglobulinaemia (elevated levels of gamma globulin): 9 people, 42.86%
Pain: 3 people, 14.29%
Neuropathy Peripheral (surface nerve damage): 3 people, 14.29%
Immune System Disorder: 3 people, 14.29%
High Blood Pressure: 3 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 14.29%
Sleep Disorder: 2 people, 9.52%
Migraine (headache): 2 people, 9.52%
Irritable Bowel Syndrome: 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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