Robaxin and Pentasa drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robaxin (methocarbamol) and Pentasa (mesalamine). Common drug interactions include cystitis among females.

The phase IV clinical study analyzes what interactions people have when they take Robaxin and Pentasa. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.

What is Robaxin?

Robaxin has active ingredients of methocarbamol. It is often used in muscle spasms. eHealthMe is studying from 9,109 Robaxin users. Check the latest studies of Robaxin.

What is Pentasa?

Pentasa has active ingredients of mesalamine. It is often used in crohn's disease. eHealthMe is studying from 23,325 Pentasa users. Check the latest studies of Pentasa.

On Jul, 20, 2026

29 people who take Robaxin and Pentasa together, and have interactions are studied.

What are the common drug interactions of Robaxin and Pentasa, by gender? *:

female:

Cystitis (inflammation of the wall of the bladder)
Drug ineffective
Arthropathy
Blood pressure fluctuation
Fistula (an abnormal connection or passageway between two)
Gait disturbance
General physical health deterioration (weak health status)
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Joint injury

male:

n/a

What are the common drug interactions of Robaxin and Pentasa, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Agitation (state of anxiety or nervous excitement)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Chest pain
Headache (pain in head)
Influenza like illness
Nausea (feeling of having an urge to vomit)
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pyrexia (fever)
Sinus congestion (blockage of sinus)
Sinusitis (inflammation of sinus)

40-49:

Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
Tinnitus (a ringing in the ears)

50-59:

Headache (pain in head)
Histoplasmosis disseminated (respiratory infection caused by inhaling the spores of the fungus histoplasma capsulatum)
Immune system disorder
Intestinal obstruction
Intestinal stenosis (partial obstruction that causes the centre opening of the intestine to become narrower)
Nasopharyngitis (inflammation of the nasopharynx)
Platelet count decreased
Pyrexia (fever)

60+:

Diarrhoea
Drug ineffective
Hypertension (high blood pressure)
Insomnia (sleeplessness)
Joint injury
Malaise (a feeling of general discomfort or uneasiness)
Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath)
Musculoskeletal disorder (disease of the body's muscles, joints, tendons, ligaments and nerves)
Poor venous access
Respiratory rate decreased (less breathing rate/min)

What are the existing conditions these people have? *

Urinary Tract Infection: 4 people, 13.79%
Pain: 3 people, 10.34%
Drug Ineffective: 3 people, 10.34%
Neuropathy Peripheral (surface nerve damage): 2 people, 6.90%
Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 6.90%
Hypersensitivity: 2 people, 6.90%
Depression: 2 people, 6.90%

* Approximation only. Some reports may have incomplete information.

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