Robinul and Nuplazid drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robinul (glycopyrrolate) and Nuplazid (pimavanserin tartrate). Common drug interactions include memory impairment among females and hallucination among males.

The phase IV clinical study analyzes what interactions people have when they take Robinul and Nuplazid. It is created by eHealthMe based on reports of 24 people who take the same drugs from the FDA, and is updated regularly.

What is Robinul?

Robinul has active ingredients of glycopyrrolate. It is often used in hyperhidrosis. eHealthMe is studying from 1,663 Robinul users. Check the latest studies of Robinul.

What is Nuplazid?

Nuplazid has active ingredients of pimavanserin tartrate. eHealthMe is studying from 47,103 Nuplazid users. Check the latest studies of Nuplazid.



On Jul, 14, 2026

24 people who take Robinul and Nuplazid together, and have interactions are studied.

Robinul and Nuplazid drug interactions.

What are the common drug interactions of Robinul and Nuplazid, by gender? *:

female:

  1. Memory impairment
  2. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  3. General physical health deterioration (weak health status)
  4. Parkinson's disease

male:

  1. Hallucination (an experience involving the perception of something not present)
  2. Death
  3. Drug ineffective
  4. Urinary tract infection
  5. Fall
  6. Hallucination, visual (seeing things that aren't there)
  7. Hypotension (abnormally low blood pressure)
  8. Loss of consciousness
  9. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  10. Rash vesicular (rash with a small bubble)

What are the common drug interactions of Robinul and Nuplazid, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Drug ineffective
  2. Hallucination (an experience involving the perception of something not present)

60+:

  1. Hallucination (an experience involving the perception of something not present)
  2. Death
  3. Fall
  4. Oedema peripheral (superficial swelling)
  5. Hypotension (abnormally low blood pressure)
  6. Loss of consciousness
  7. Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
  8. Rash vesicular (rash with a small bubble)
  9. Seborrhoeic dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp)
  10. Anxiety

What are the existing conditions these people have? *

  1. Parkinson's Disease: 13 people, 54.17%
  2. Hallucinations (sensations that appear real but are created by your mind): 8 people, 33.33%
  3. Delusion (a false belief or opinion): 8 people, 33.33%
  4. Stress And Anxiety: 3 people, 12.50%
  5. Salivary Hypersecretion (excess saliva secretion): 3 people, 12.50%
  6. Dyspnea (difficult or laboured breathing): 3 people, 12.50%
  7. Wheezing (a high-pitched whistling sound made while you breath): 2 people, 8.33%
  8. Pain: 2 people, 8.33%
  9. On And Off Phenomenon: 2 people, 8.33%
  10. Drooling (drop saliva uncontrollably from the mouth): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Robinul and Nuplazid?

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- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Robinul and Nuplazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robinul:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nuplazid:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robinul and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nuplazid and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on glycopyrrolate and pimavanserin tartrate (the active ingredients of Robinul and Nuplazid, respectively), and Robinul and Nuplazid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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