Robitussin and Lanoxin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robitussin (guaifenesin) and Lanoxin (digoxin). Common drug interactions include arteriosclerosis among females and cough among males.

The phase IV clinical study analyzes what interactions people have when they take Robitussin and Lanoxin. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Lanoxin?

Lanoxin has active ingredients of digoxin. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 21,852 Lanoxin users. Check the latest studies of Lanoxin.

On Aug, 08, 2026

19 people who take Robitussin and Lanoxin together, and have interactions are studied.

Robitussin and Lanoxin drug interactions.

What are the common drug interactions of Robitussin and Lanoxin, by gender? *:

female:

Arteriosclerosis (thickening and hardening of arteries)
Blood urea increased
Cardiac arrest
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Debility (physical weakness)
Diarrhoea
Digoxin toxicity
Drug maladministration
Flushing (the warm, red condition of human skin)
Fungal infection

male:

Cough
Foetal exposure during pregnancy (exposing your unborn child to contraindicated in pregnancy leads birth defect)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram st segment elevation
Extrasystoles
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Glucose tolerance impaired (blood glucose is raised beyond normal levels, but not high enough to warrant a diabetes diagnosis)
Hypercapnia (too much smoke)
Hyperhidrosis (abnormally increased sweating)
Rash maculo-papular (red area on the skin that is covered with small confluent bumps)

What are the common drug interactions of Robitussin and Lanoxin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Diarrhoea
Fungal infection
Headache (pain in head)
Lung disorder (lung disease)
Neck pain
Pain in jaw

50-59:

Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Tachypnoea (a condition of rapid breathing over 20 per minute)
Thrombocytosis
Viral infection
Vomiting
Weight increased
Wheezing (a high-pitched whistling sound made while you breath)
White blood cell count increased
Hospitalisation
Oropharyngeal pain

60+:

Hypotension (abnormally low blood pressure)
Pyrexia (fever)
Oral candidiasis (fungal infection of mouth)
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Platelet count decreased
Rales (an abnormal respiratory sound characterized by fine crackles)
Rhonchi (abnormal breath sounds)
Sepsis (a severe blood infection that can lead to organ failure and death)
Appetite decreased (decreased appetite occurs when you have a reduced desire to eat)
Arteriosclerosis (thickening and hardening of arteries)

What are the existing conditions these people have? *

Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 15.79%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 5.26%
Pain: 1 person, 5.26%
Emotional Distress: 1 person, 5.26%
Birth Control: 1 person, 5.26%
Autonomic Failure Syndrome (a degenerative disease of the autonomic nervous system): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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