Robitussin and Ventolin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Robitussin (guaifenesin) and Ventolin (albuterol). Common drug interactions include cough among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Robitussin and Ventolin. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Robitussin?

Robitussin has active ingredients of guaifenesin. eHealthMe is studying from 3,532 Robitussin users. Check the latest studies of Robitussin.

What is Ventolin?

Ventolin has active ingredients of albuterol. It is often used in asthma. eHealthMe is studying from 51,849 Ventolin users. Check the latest studies of Ventolin.



On Jul, 16, 2026

36 people who take Robitussin and Ventolin together, and have interactions are studied.

Robitussin and Ventolin drug interactions.

What are the common drug interactions of Robitussin and Ventolin, by gender? *:

female:

  1. Cough
  2. Headache (pain in head)
  3. Cystic fibrosis (disease of the secretary glands)
  4. Decreased appetite
  5. Diarrhoea
  6. Dyspnoea (difficult or laboured respiration)
  7. Fatigue (feeling of tiredness)
  8. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  9. Lung neoplasm malignant (cancer tumour of lung)
  10. Metastatic neoplasm (spreadable cancer tumour)

male:

  1. Drug ineffective
  2. Aphonia (inability to produce voice)
  3. Head injury
  4. Headache (pain in head)
  5. Influenza like illness
  6. Malaise (a feeling of general discomfort or uneasiness)
  7. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  8. Productive cough
  9. Rhinorrhoea (watery mucus discharge from the nose)
  10. Cardiac failure congestive

What are the common drug interactions of Robitussin and Ventolin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Cough
  2. Cystic fibrosis (disease of the secretary glands)
  3. Decreased appetite
  4. Diarrhoea
  5. Dyspnoea (difficult or laboured respiration)
  6. Fatigue (feeling of tiredness)
  7. Headache (pain in head)
  8. Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
  9. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  10. Pyrexia (fever)

20-29:

  1. Abdominal pain lower
  2. Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
  3. Depression
  4. Dysmenorrhoea (painful menstruation)
  5. Ectopic pregnancy (a pregnancy in which the foetus develops outside the uterus, typically in a fallopian tube)
  6. Haemoperitoneum (presence of blood in the peritoneal cavity)
  7. Impaired healing
  8. Injection site rash
  9. Menometrorrhagia (a condition in which prolonged or excessive uterine bleeding occurs irregularly and more frequently than normal)
  10. Menstruation irregular

30-39:

  1. Acute respiratory failure
  2. General physical health deterioration (weak health status)
  3. H1n1 influenza (flu (influenza), which is caused by virus influenza a (h1n1))
  4. Neck pain
  5. Oedema peripheral (superficial swelling)
  6. Sepsis (a severe blood infection that can lead to organ failure and death)
  7. Thrombosis (formation of a blood clot inside a blood vessel)
  8. Wound dehiscence (a surgical incision reopens either internally or externally)

40-49:

  1. Oedema peripheral (superficial swelling)
  2. Pain in extremity
  3. Pneumonia
  4. Thrombosis (formation of a blood clot inside a blood vessel)
  5. Transient ischaemic attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow))
  6. Vision blurred

50-59:

  1. Drug ineffective
  2. Anaphylactic reaction (serious allergic reaction)
  3. Cough
  4. Dysgeusia (disorder of the sense of taste)
  5. Feeling jittery
  6. Lower respiratory tract infection
  7. Oropharyngeal pain
  8. Pneumonia
  9. Productive cough
  10. Respiratory tract irritation

60+:

  1. Death
  2. Fall
  3. Inflammation
  4. Limb injury
  5. Neoplasm malignant (cancer tumour)
  6. Peripheral swelling
  7. Peritoneal haemorrhage (peritoneal bleeding)
  8. Pollakiuria (abnormally frequent passage of relatively small quantities or urine)
  9. Urinary tract obstruction
  10. Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)

What are the existing conditions these people have? *

  1. Cough: 8 people, 22.22%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 4 people, 11.11%
  3. Multiple Myeloma (cancer of the plasma cells): 4 people, 11.11%
  4. Infective Pulmonary Exacerbation Of Cystic Fibrosis (severe infective lung disease with production of abnormally thick mucus): 3 people, 8.33%
  5. Blood Potassium Decreased: 3 people, 8.33%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 8.33%
  7. Hyperglycemia (high blood sugar): 3 people, 8.33%
  8. Constipation: 3 people, 8.33%
  9. Vulvovaginal Candidiasis (vulvovaginal infection by fungi): 3 people, 8.33%
  10. Liver Disorder (liver diseases): 3 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Robitussin and Ventolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Robitussin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Ventolin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Robitussin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Ventolin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on guaifenesin and albuterol (the active ingredients of Robitussin and Ventolin, respectively), and Robitussin and Ventolin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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