Rocephin and Sumatriptan drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rocephin (ceftriaxone sodium) and Sumatriptan (sumatriptan succinate). Common drug interactions include anxiety among females and asthenia among males.

The phase IV clinical study analyzes what interactions people have when they take Rocephin and Sumatriptan. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Rocephin?

Rocephin has active ingredients of ceftriaxone sodium. It is often used in infection. eHealthMe is studying from 15,665 Rocephin users. Check the latest studies of Rocephin.

What is Sumatriptan?

Sumatriptan has active ingredients of sumatriptan succinate. It is often used in migraine. eHealthMe is studying from 18,159 Sumatriptan users. Check the latest studies of Sumatriptan.



On Jul, 28, 2026

15 people who take Rocephin and Sumatriptan together, and have interactions are studied.

Rocephin and Sumatriptan drug interactions.

What are the common drug interactions of Rocephin and Sumatriptan, by gender? *:

female:

  1. Anxiety
  2. Chronic kidney disease
  3. Renal failure (kidney dysfunction)
  4. Pulmonary embolism (blockage of the main artery of the lung)
  5. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  6. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  7. Depression
  8. Fibromyalgia (a long-term condition which causes pain all over the body)
  9. Headache (pain in head)
  10. Mania (a state of abnormally elevated or irritable mood)

male:

  1. Asthenia (weakness)
  2. Chest discomfort
  3. Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
  4. Night sweats (sweating in night)
  5. Productive cough
  6. Pruritus (severe itching of the skin)
  7. Pseudomonas test positive
  8. Pyrexia (fever)
  9. Secretion discharge
  10. Sputum discoloured

What are the common drug interactions of Rocephin and Sumatriptan, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
  2. Thrombophlebitis superficial (swelling (inflammation) of a superficial vein caused by a blood clot)

30-39:

  1. Anxiety
  2. Chronic kidney disease
  3. Renal failure (kidney dysfunction)
  4. Asthenia (weakness)
  5. Bipolar i disorder (mood disorder that is characterized by at least one manic or mixed episode)
  6. Chest discomfort
  7. Chest pain
  8. Cough
  9. Decreased appetite
  10. Diarrhoea

40-49:

  1. Pulmonary embolism (blockage of the main artery of the lung)
  2. Drug ineffective

50-59:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)

60+:

  1. Activated partial thromboplastin time prolonged
  2. Alanine aminotransferase increased
  3. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low)
  4. Hypocalcaemia (levels of calcium in blood serum are abnormally low)
  5. Hypotension (abnormally low blood pressure)
  6. Hypoxia (low oxygen in tissues)
  7. International normalised ratio increased
  8. Pancreatitis (inflammation of pancreas)
  9. Proteinuria (presence of protein in the urine)
  10. Pyrexia (fever)

What are the existing conditions these people have? *

  1. Pain: 8 people, 53.33%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 7 people, 46.67%
  3. Sleep Disorder: 5 people, 33.33%
  4. Stress And Anxiety: 4 people, 26.67%
  5. Depression: 4 people, 26.67%
  6. High Blood Pressure: 4 people, 26.67%
  7. Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 26.67%
  8. Headache (pain in head): 3 people, 20.00%
  9. Muscle Spasms (muscle contraction): 3 people, 20.00%
  10. Nausea (feeling of having an urge to vomit): 3 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rocephin and Sumatriptan:

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Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rocephin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Sumatriptan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rocephin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Sumatriptan and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on ceftriaxone sodium and sumatriptan succinate (the active ingredients of Rocephin and Sumatriptan, respectively), and Rocephin and Sumatriptan (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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