Rogaine and Prolia drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rogaine (minoxidil) and Prolia (denosumab). Common drug interactions include drug ineffective among females.

The phase IV clinical study analyzes what interactions people have when they take Rogaine and Prolia. It is created by eHealthMe based on reports of 25 people who take the same drugs from the FDA, and is updated regularly.

What is Rogaine?

Rogaine has active ingredients of minoxidil. It is often used in hair loss. eHealthMe is studying from 34,083 Rogaine users. Check the latest studies of Rogaine.

What is Prolia?

Prolia has active ingredients of denosumab. It is often used in osteoporosis. eHealthMe is studying from 151,388 Prolia users. Check the latest studies of Prolia.



On Jul, 20, 2026

25 people who take Rogaine and Prolia together, and have interactions are studied.

Rogaine and Prolia drug interactions.

What are the common drug interactions of Rogaine and Prolia, by gender? *:

female:

  1. Drug ineffective
  2. Pruritus (severe itching of the skin)
  3. Lipoma (a growth of fatty tissue that slowly develops just under your skin)
  4. Mitochondrial myopathy (the muscle fibres do not function due to damage of mitochondria)
  5. Periodontal disease (disease that attacks the gum and bone and around the teeth)
  6. Seborrhoeic dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp)
  7. Skin exfoliation (removal of the oldest dead skin cells)
  8. Visual impairment
  9. Alopecia universalis (rapid loss of all hair, including eyebrows and eyelashes)
  10. Arthralgia (joint pain)

male:

n/a

What are the common drug interactions of Rogaine and Prolia, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

  1. Drug ineffective
  2. Back pain
  3. Seborrhoeic dermatitis (a common, inflammatory skin condition that causes flaky, white to yellowish scales to form on oily areas such as the scalp)
  4. Visual impairment
  5. Pruritus (severe itching of the skin)
  6. Alopecia universalis (rapid loss of all hair, including eyebrows and eyelashes)
  7. Arthralgia (joint pain)
  8. Joint stiffness
  9. Myalgia (muscle pain)
  10. Blood pressure increased

What are the existing conditions these people have? *

  1. Pain: 3 people, 12.00%
  2. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 3 people, 12.00%
  3. Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 12.00%
  4. Bone Disorder: 3 people, 12.00%
  5. Urinary Tract Infection: 2 people, 8.00%
  6. Multiple Allergies (allergy to multiple agents): 2 people, 8.00%
  7. Indigestion: 2 people, 8.00%
  8. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 2 people, 8.00%
  9. High Blood Cholesterol: 2 people, 8.00%
  10. Depression: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Rogaine and Prolia?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rogaine and Prolia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rogaine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prolia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rogaine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prolia and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on minoxidil and denosumab (the active ingredients of Rogaine and Prolia, respectively), and Rogaine and Prolia (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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