Rosiglitazone and Tysabri drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rosiglitazone (rosiglitazone maleate) and Tysabri (natalizumab). Common drug interactions include type 2 diabetes mellitus among females and arteriosclerosis coronary artery among males.

The phase IV clinical study analyzes what interactions people have when they take Rosiglitazone and Tysabri. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Rosiglitazone?

Rosiglitazone has active ingredients of rosiglitazone maleate. eHealthMe is studying from 4,700 Rosiglitazone users. Check the latest studies of Rosiglitazone.

What is Tysabri?

Tysabri has active ingredients of natalizumab. It is often used in multiple sclerosis. eHealthMe is studying from 221,369 Tysabri users. Check the latest studies of Tysabri.

eHealthMe: drug outcomes in the real world

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On Jul, 03, 2026

13 people who take Rosiglitazone and Tysabri together, and have interactions are studied.

Rosiglitazone and Tysabri drug interactions.

What are the common drug interactions of Rosiglitazone and Tysabri, by gender? *:

female:

Type 2 diabetes mellitus
Vasculitis (inflammation of a blood vessel or blood vessels)
Viral infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Stent placement
Angioplasty
Aphasia (damage to the parts of the brain that control language)
Arterial stenosis (abnormal narrowing of the aortic valve in the heart)
Brain injury

male:

Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Death
Heart valve incompetence (heart's valves do not work correctly)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Cardiovascular disorder (heart diseases)
Pericardial effusion (fluid around the heart)
Urinary tract infection

What are the common drug interactions of Rosiglitazone and Tysabri, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Agitation (state of anxiety or nervous excitement)
Aphasia (damage to the parts of the brain that control language)
Constipation
Fatigue (feeling of tiredness)
Hemiparesis (weakness on one side of the body)
Hyperphagia (an abnormal appetite for food)
Hypertension (high blood pressure)
Hypoaesthesia (reduced sense of touch or sensation)
Insomnia (sleeplessness)
Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)

40-49:

Immune system disorder
Type 2 diabetes mellitus
Vasculitis (inflammation of a blood vessel or blood vessels)
Viral infection
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Death
Arteriosclerosis coronary artery (thickening and hardening of arteries- coronary artery)
Atrioventricular block first degree (heart block first degree)
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Heart valve incompetence (heart's valves do not work correctly)

50-59:

Acute myocardial infarction (acute heart attack)
Bladder squamous cell carcinoma stage unspecified (bladder squamous cell cancer stage unspecified)
Cardiac failure congestive
Cardiovascular disorder (heart diseases)
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Death
Malaise (a feeling of general discomfort or uneasiness)
Malignant melanoma (skin cancer rises from melancytes)
Metastatic malignant melanoma (spreadable cancer tumour of melanine)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)

60+:

Aphasia (damage to the parts of the brain that control language)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Cardiac failure congestive
Cardiovascular disorder (heart diseases)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Pericardial effusion (fluid around the heart)
Retinal exudates (discharge from retina)
Retinopathy (acute damage to the retina of the eye)
Urinary tract infection

What are the existing conditions these people have? *

Diabetes: 9 people, 69.23%
Type 2 Diabetes: 2 people, 15.38%
Vasculitis (inflammation of a blood vessel or blood vessels): 1 person, 7.69%
Migraine (headache): 1 person, 7.69%
Gait Disturbance: 1 person, 7.69%
Hepatitis C: 1 person, 7.69%
High Blood Pressure: 1 person, 7.69%
Immune System Disorder: 1 person, 7.69%
Lung Infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung): 1 person, 7.69%
Nausea (feeling of having an urge to vomit): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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