Rowasa and Accutane drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rowasa (mesalamine) and Accutane (isotretinoin). Common drug interactions include pyrexia among females and gastrointestinal disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Rowasa and Accutane. It is created by eHealthMe based on reports of 23 people who take the same drugs from the FDA, and is updated regularly.

What is Rowasa?

Rowasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 943 Rowasa users. Check the latest studies of Rowasa.

What is Accutane?

Accutane has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 35,221 Accutane users. Check the latest studies of Accutane.

On Aug, 05, 2026

23 people who take Rowasa and Accutane together, and have interactions are studied.

What are the common drug interactions of Rowasa and Accutane, by gender? *:

female:

Pyrexia (fever)
Rectal tenesmus (a feeling of incomplete defecation)
Red blood cell count decreased
Seasonal allergy (allergic condition due to certain season)
Serum ferritin increased
Vitamin b12 increased
Vomiting
Weight decreased
Wheezing (a high-pitched whistling sound made while you breath)
Depression

male:

Gastrointestinal disorder (functional problems of gastrointestinal tract)
Haematochezia (passage of stools containing blood)
Depression
Dermal cyst
Pain in extremity
Post procedural complication
Stress
Swelling
Vitiligo (pigment is lost from areas of the skin)
Abdominal pain

What are the common drug interactions of Rowasa and Accutane, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Vitiligo (pigment is lost from areas of the skin)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Emotional distress
Inflammatory bowel disease
Irritable bowel syndrome

20-29:

Post procedural complication
Swelling
Abdominal pain
Colitis (inflammation of colon)
Depression
Diarrhoea haemorrhagic (bloody diarrhoea)
Dyspepsia (indigestion)
Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
Frequent bowel movements
Haematocrit decreased

30-39:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Depression
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Inflammatory bowel disease
Malignant melanoma (skin cancer rises from melancytes)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure acute (rapid kidney dysfunction)
Uveitis (inflammation of the uvea)
Myalgia (muscle pain)
Headache (pain in head)

40-49:

n/a

50-59:

Depression
Inflammatory bowel disease
Fatigue (feeling of tiredness)
Generalised anxiety disorder (excessive, uncontrollable, unexplained and often irrational worry)
Headache (pain in head)
Immunosuppressant drug level increased
Infection
Malignant melanoma (skin cancer rises from melancytes)
Muscular weakness (muscle weakness)
Myalgia (muscle pain)

60+:

n/a

What are the existing conditions these people have? *

Upper Respiratory Tract Infection: 11 people, 47.83%
Kidney Infection (Pyelonephritis): 11 people, 47.83%
Depression: 11 people, 47.83%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 47.83%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 47.83%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 5 people, 21.74%
Asthma: 4 people, 17.39%

* Approximation only. Some reports may have incomplete information.

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