Rowasa and Paxil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rowasa (mesalamine) and Paxil (paroxetine hydrochloride). Common drug interactions include headache among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Rowasa and Paxil. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Rowasa?

Rowasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 943 Rowasa users. Check the latest studies of Rowasa.

What is Paxil?

Paxil has active ingredients of paroxetine hydrochloride. It is often used in depression. eHealthMe is studying from 92,546 Paxil users. Check the latest studies of Paxil.

On Jul, 14, 2026

14 people who take Rowasa and Paxil together, and have interactions are studied.

What are the common drug interactions of Rowasa and Paxil, by gender? *:

female:

Headache (pain in head)
Muscular weakness (muscle weakness)
Pain in extremity
Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Haemorrhoids (a swollen vein or group of veins in the region of the anus)
Hyperkeratosis (thickening of the outer layer of the skin)
Muscle twitching
Pharyngitis (inflammation of the pharynx, causing a sore throat)

male:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Renal failure (kidney dysfunction)

What are the common drug interactions of Rowasa and Paxil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Inflammatory bowel disease
Malignant melanoma (skin cancer rises from melancytes)
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure acute (rapid kidney dysfunction)
Uveitis (inflammation of the uvea)
Myalgia (muscle pain)
Headache (pain in head)
Muscular weakness (muscle weakness)
Pain in extremity

40-49:

Abdominal pain

50-59:

Blood creatinine increased
Blood urea increased
Muscular weakness (muscle weakness)
Myalgia (muscle pain)
Pain in extremity
Pyelonephritis (inflammation of kidney caused by bacteria)
Renal failure acute (rapid kidney dysfunction)
Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
Uveitis (inflammation of the uvea)
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)

60+:

n/a

What are the existing conditions these people have? *

Upper Respiratory Tract Infection: 11 people, 78.57%
Kidney Infection (Pyelonephritis): 11 people, 78.57%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 11 people, 78.57%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 11 people, 78.57%
Acne (skin problems that cause pimples): 11 people, 78.57%
Pharyngitis (inflammation of the pharynx, causing a sore throat): 5 people, 35.71%
Pain: 1 person, 7.14%
Nausea (feeling of having an urge to vomit): 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Stress And Anxiety: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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