Rowasa and Prednisolone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rowasa (mesalamine) and Prednisolone (prednisolone). Common drug interactions include abdominal pain among females and gastrointestinal disorder among males.

The phase IV clinical study analyzes what interactions people have when they take Rowasa and Prednisolone. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Rowasa?

Rowasa has active ingredients of mesalamine. It is often used in ulcerative colitis. eHealthMe is studying from 943 Rowasa users. Check the latest studies of Rowasa.

What is Prednisolone?

Prednisolone has active ingredients of prednisolone. It is often used in rheumatoid arthritis. eHealthMe is studying from 212,675 Prednisolone users. Check the latest studies of Prednisolone.



On Aug, 01, 2026

21 people who take Rowasa and Prednisolone together, and have interactions are studied.

Rowasa and Prednisolone drug interactions.

What are the common drug interactions of Rowasa and Prednisolone, by gender? *:

female:

  1. Abdominal pain
  2. Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
  3. Back pain
  4. Blast crisis in myelogenous leukaemia
  5. Blood magnesium decreased
  6. Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
  7. Loose stools
  8. Musculoskeletal pain (pain affects the bones, muscles, ligaments, tendons, and nerves)
  9. Tonsillitis (inflammation of tonsil)
  10. Weight decreased

male:

  1. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  2. Inflammation
  3. Anaemia (lack of blood)
  4. Blood creatinine increased
  5. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  6. Dermal cyst
  7. Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
  8. Erythrocyte sedimentation rate increased
  9. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  10. Headache (pain in head)

What are the common drug interactions of Rowasa and Prednisolone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Chronic obstructive airways disease
  2. Colitis (inflammation of colon)
  3. Decreased appetite
  4. Dyspnoea (difficult or laboured respiration)
  5. Hypersensitivity
  6. Lung disorder (lung disease)
  7. Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung)
  8. Pancreatitis acute (sudden inflammation of pancreas)
  9. Po2 decreased
  10. Proctocolitis (inflammation of the rectum and colon)

20-29:

  1. Blood iron decreased
  2. Cholecystitis (infection of gallbladder)
  3. Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
  4. Gastrointestinal disorder (functional problems of gastrointestinal tract)
  5. Haematochezia (passage of stools containing blood)
  6. Lymphadenopathy (disease or enlargement of lymph nodes)
  7. Nausea (feeling of having an urge to vomit)
  8. Actinic keratosis (skin disease due to sun exposure)
  9. Dermal cyst
  10. Pain in extremity

30-39:

  1. Hepatitis (inflammation of the liver)
  2. Inflammation
  3. Interstitial lung disease
  4. Chronic kidney disease
  5. Nephrogenic anaemia (anaemia due to kidney disease)
  6. Renal failure (kidney dysfunction)

40-49:

n/a

50-59:

n/a

60+:

  1. Anaemia (lack of blood)
  2. Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
  3. Colonic perforation (a hole in the colon)
  4. Colonoscopy
  5. Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
  6. Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body)
  7. Drug rash with eosinophilia and systemic symptoms (adverse drug reactions with rash)
  8. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  9. Hypertrophy (increase in the volume of an organ or tissue due to the enlargement of its component cells)
  10. Ileus (a painful obstruction of the ileum or other part of the intestine)

What are the existing conditions these people have? *

  1. Asthma: 4 people, 19.05%
  2. Acne (skin problems that cause pimples): 4 people, 19.05%
  3. Productive Cough: 2 people, 9.52%
  4. Enterocolitis Haemorrhagic (bleeding and inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon): 2 people, 9.52%
  5. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

Do you take Rowasa and Prednisolone?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Rowasa and Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rowasa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Prednisolone:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rowasa and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prednisolone and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on mesalamine and prednisolone (the active ingredients of Rowasa and Prednisolone, respectively), and Rowasa and Prednisolone (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: