Roxanol and Coreg drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxanol (morphine sulfate) and Coreg (carvedilol). Common drug interactions include bronchitis among females and pain among males.

The phase IV clinical study analyzes what interactions people have when they take Roxanol and Coreg. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Roxanol?

Roxanol has active ingredients of morphine sulfate. eHealthMe is studying from 807 Roxanol users. Check the latest studies of Roxanol.

What is Coreg?

Coreg has active ingredients of carvedilol. It is often used in high blood pressure. eHealthMe is studying from 49,583 Coreg users. Check the latest studies of Coreg.



On Jul, 17, 2026

20 people who take Roxanol and Coreg together, and have interactions are studied.

Roxanol and Coreg drug interactions.

What are the common drug interactions of Roxanol and Coreg, by gender? *:

female:

  1. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  2. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  3. Cardiac failure
  4. Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
  5. Cardioactive drug level increased
  6. Cardiomegaly (increased size of heart than normal)
  7. Chest discomfort
  8. Chronic kidney disease
  9. Cough
  10. Crying

male:

  1. Pain
  2. Constipation
  3. Arthralgia (joint pain)
  4. Burning sensation
  5. Dry skin
  6. Erythema (redness of the skin)
  7. Fibrosis (formation of excess fibrous connective tissue in an organ or tissue)
  8. Gait disturbance
  9. Hypoaesthesia (reduced sense of touch or sensation)
  10. Injury

What are the common drug interactions of Roxanol and Coreg, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Application site burn
  2. Caustic injury
  3. Chemical burn of skin

50-59:

  1. Oesophageal carcinoma (cancer tumour of oesophagus)
  2. Secretion discharge
  3. Weight decreased
  4. Ascites (accumulation of fluid in the abdominal cavity)
  5. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
  6. Chest pain
  7. Colon cancer
  8. Crying
  9. Haemoptysis (blood-stained sputum from the bronchi, larynx, trachea, or lungs)
  10. Hyperkalaemia (damage to or disease of the kidney)

60+:

  1. Anaemia (lack of blood)
  2. Injury
  3. Dizziness
  4. Ejection fraction decreased (systolic heart failure)
  5. Fatigue (feeling of tiredness)
  6. Hypotension (abnormally low blood pressure)
  7. Pain
  8. Renal failure (kidney dysfunction)
  9. Arthralgia (joint pain)
  10. Burning sensation

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 4 people, 20.00%
  2. Arrhythmias (irregular heartbeat): 4 people, 20.00%
  3. Pain: 3 people, 15.00%
  4. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 15.00%
  5. Depression: 3 people, 15.00%
  6. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
  7. Constipation: 2 people, 10.00%
  8. Diabetes: 2 people, 10.00%
  9. Nausea (feeling of having an urge to vomit): 2 people, 10.00%
  10. Dyspnea (difficult or laboured breathing): 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Roxanol and Coreg?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Roxanol and Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Roxanol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Coreg:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Roxanol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Coreg and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on morphine sulfate and carvedilol (the active ingredients of Roxanol and Coreg, respectively), and Roxanol and Coreg (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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