Roxicet and Temazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Roxicet (acetaminophen; oxycodone hydrochloride) and Temazepam (temazepam). Common drug interactions include nausea among females and chest pain among males.
The phase IV clinical study analyzes what interactions people have when they take Roxicet and Temazepam. It is created by eHealthMe based on reports of 91 people who take the same drugs from the FDA, and is updated regularly.
What is Roxicet?
Roxicet has active ingredients of acetaminophen; oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 2,254 Roxicet users. Check the latest studies of Roxicet.
What is Temazepam?
Temazepam has active ingredients of temazepam. It is often used in insomnia. eHealthMe is studying from 42,106 Temazepam users. Check the latest studies of Temazepam.
91 people who take Roxicet and Temazepam together, and have interactions are studied.

What are the common drug interactions of Roxicet and Temazepam, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Injury
- Bone disorder
- Dental caries
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Facial pain
- Groin pain
- Intervertebral disc disorder (spinal disc disorder)
- Leukopenia (less number of white blood cells in blood)
male:
- Chest pain
- Anxiety
- Injury
- Metastases to lymph nodes (cancer spreads to lymph node)
- Neck pain
- Pain in extremity
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anosmia (partial or complete loss of the sense of smell)
- Arthralgia (joint pain)
What are the common drug interactions of Roxicet and Temazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Abdominal pain
- Asthenia (weakness)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Coma (state of unconsciousness lasting more than six hours)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Drug level increased
- Hepatic steatosis (fatty liver disease)
- Metabolic disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues)
- Pancreatic necrosis (death of pancreas tissue in pancreas)
- Pancreatitis haemorrhagic (inflammation of pancreas with bleeding)
30-39:
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Chronic kidney disease
- Nephrogenic anaemia (anaemia due to kidney disease)
- Blood creatinine increased
- Blood urea increased
- Cardiac failure congestive
- Death
- Disease progression
- Disseminated intravascular coagulation (systemic activation of blood coagulation)
40-49:
- Drug ineffective
- Drug withdrawal syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation)
- Oedema peripheral (superficial swelling)
- Anxiety
- Cellulitis (infection under the skin)
- Depression
- Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
- Drug dependence
- Nephrolithiasis (calculi in the kidneys)
- Ovarian cyst (fluid filled sac of the ovary)
50-59:
- Nausea (feeling of having an urge to vomit)
- Pyrexia (fever)
- Abscess (pus)
- Asthma
- Bone pain
- Chills (felling of cold)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe)
- Fatigue (feeling of tiredness)
- Fistula (an abnormal connection or passageway between two)
60+:
- Anxiety
- Injury
- Oedema peripheral (superficial swelling)
- Osteonecrosis of jaw (death of bone of jaw)
- Anaemia (lack of blood)
- Dental caries
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dysphonia (speech disorder attributable to a disorder of phonation)
- Facial pain
- Groin pain
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 15 people, 16.48%
- Muscle Spasms (muscle contraction): 14 people, 15.38%
- Depression: 10 people, 10.99%
- Bone Density Abnormal: 9 people, 9.89%
- Prostate Cancer: 9 people, 9.89%
- Sleep Disorder: 8 people, 8.79%
- High Blood Pressure: 8 people, 8.79%
- Cardiac Disorder: 6 people, 6.59%
- Urinary Incontinence (inability to control the flow of urine and involuntary urination): 6 people, 6.59%
- Urinary Tract Infection: 5 people, 5.49%
* Approximation only. Some reports may have incomplete information.
Do you take Roxicet and Temazepam?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Roxicet and Temazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Roxicet:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Temazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Roxicet and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Temazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on acetaminophen; oxycodone hydrochloride and temazepam (the active ingredients of Roxicet and Temazepam, respectively), and Roxicet and Temazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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