Trazodone hydrochloride and Hyperreflexia - a phase IV clinical study of FDA data

Summary:

Hyperreflexia is reported as a side effect among people who take Trazodone hydrochloride (trazodone hydrochloride), especially for people who are male, 60+ old, also take Mirtazapine, and have Paranoia.

The phase IV clinical study analyzes which people have Hyperreflexia when taking Trazodone hydrochloride. It is created by eHealthMe based on reports of 17,393 people who have side effects when taking Trazodone hydrochloride from the FDA, and is updated regularly.

What is Trazodone hydrochloride?

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. eHealthMe is studying from 23,016 Trazodone hydrochloride users. Check the latest studies of Trazodone hydrochloride.

What is Hyperreflexia?

Hyperreflexia (overactive or over responsive reflexes) is found to be associated with 429 drugs and 649 conditions by eHealthMe. Check the latest studies of Hyperreflexia.

On Jul, 07, 2026

17,393 people reported to have side effects when taking Trazodone hydrochloride.
Among them, 11 people (0.06%) have Hyperreflexia.

Could Trazodone hydrochloride cause Hyperreflexia?

Among these 11 people:

What is the gender of people who have Hyperreflexia when taking Trazodone hydrochloride? *

female: 45.45 %
male: 54.55 %

What is the age of people who have Hyperreflexia when taking Trazodone hydrochloride? *

What are other drugs people take besides Trazodone hydrochloride? *

What are other side effects people have besides Hyperreflexia? *

Serotonin Syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time): 9 people, 81.82%
Blood Creatine Phosphokinase Increased: 5 people, 45.45%
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles): 5 people, 45.45%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 36.36%
Hypertonia (abnormal increase in muscle tension and a reduced ability of a muscle to stretch): 4 people, 36.36%
Confusional State: 4 people, 36.36%
Arrhythmias (irregular heartbeat): 4 people, 36.36%
Fever: 3 people, 27.27%
Blood Creatinine Increased: 3 people, 27.27%
Acute Kidney Failure: 3 people, 27.27%

What are the existing conditions these people have? *

Suicide Attempt: 2 people, 18.18%
Paranoia (psychotic disorder characterized by delusions of persecution with or without grandeur): 2 people, 18.18%
Parkinson's Disease: 1 person, 9.09%
Movement - Unpredictable Or Jerky: 1 person, 9.09%
Cognitive Disorder (mental health disorders affects learning, memory, perception, and problem solving): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Trazodone hydrochloride and have Hyperreflexia?

- Check whether Hyperreflexia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Trazodone hydrochloride:

Trazodone hydrochloride (23,016 reports)

Hyperreflexia treatments and more:

Hyperreflexia (4,677 reports)

Browse all side effects of Trazodone hydrochloride:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperreflexia:

Hyperreflexia (429 drugs)

Browse all the conditions that are associated with Hyperreflexia:

Hyperreflexia (649 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on trazodone hydrochloride (the active ingredients of Trazodone hydrochloride) and Trazodone hydrochloride (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.