Roxicodone and Daptomycin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Roxicodone (oxycodone hydrochloride) and Daptomycin (daptomycin). Common drug interactions include chronic kidney disease among females and drug-induced liver injury among males.

The phase IV clinical study analyzes what interactions people have when they take Roxicodone and Daptomycin. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Roxicodone?

Roxicodone has active ingredients of oxycodone hydrochloride. It is often used in pain. eHealthMe is studying from 20,099 Roxicodone users. Check the latest studies of Roxicodone.

What is Daptomycin?

Daptomycin has active ingredients of daptomycin. eHealthMe is studying from 7,879 Daptomycin users. Check the latest studies of Daptomycin.

On Jul, 15, 2026

20 people who take Roxicodone and Daptomycin together, and have interactions are studied.

Roxicodone and Daptomycin drug interactions.

What are the common drug interactions of Roxicodone and Daptomycin, by gender? *:

female:

Chronic kidney disease
Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)

male:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Burkholderia test positive
Syncope (loss of consciousness with an inability to maintain postural tone)
Adenovirus infection
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Blood calcium decreased
Blood sodium decreased
Blood urea increased
Death

What are the common drug interactions of Roxicodone and Daptomycin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Epistaxis (bleed from the nose)
Hepatobiliary disease (diseases affect the liver and/or biliary tract)
Haemorrhage (bleeding)

30-39:

n/a

40-49:

Blood calcium decreased
Blood sodium decreased
Blood urea increased
Enterococcus test positive
Hypoxia (low oxygen in tissues)
Intestinal obstruction
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Pneumonia
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)

50-59:

Salmonellosis (an infection with salmonella bacteria)
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Adenovirus infection
Azotaemia (excess of urea or other nitrogenous compounds in the blood)
Burkholderia test positive
Death
Dyskinesia (abnormality or impairment of voluntary movement)
Femur fracture
Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
Myoclonus (a brief, involuntary twitching of a muscle or a group of muscles)

60+:

Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)
Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
Device related infection

What are the existing conditions these people have? *

High Blood Pressure: 8 people, 40.00%
Insomnia (sleeplessness): 8 people, 40.00%
Hypokalemia (low potassium): 6 people, 30.00%
Nausea (feeling of having an urge to vomit): 6 people, 30.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 30.00%
Constipation: 6 people, 30.00%
Fever: 6 people, 30.00%
Infection: 6 people, 30.00%
Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 6 people, 30.00%
Nausea And Vomiting: 4 people, 20.00%

* Approximation only. Some reports may have incomplete information.

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