Rythmol sr and Nexium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol sr (propafenone hydrochloride) and Nexium (esomeprazole magnesium). Common drug interactions include impaired gastric emptying among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol sr and Nexium. It is created by eHealthMe based on reports of 21 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol sr?

Rythmol sr has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 586 Rythmol sr users. Check the latest studies of Rythmol sr.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 15, 2026

21 people who take Rythmol sr and Nexium together, and have interactions are studied.

Rythmol sr and Nexium drug interactions.

What are the common drug interactions of Rythmol Sr and Nexium, by gender? *:

female:

Impaired gastric emptying
Insomnia (sleeplessness)
Lip swelling
Myalgia (muscle pain)
Nausea (feeling of having an urge to vomit)
Nephrolithiasis (calculi in the kidneys)
Palpitations (feelings or sensations that your heart is pounding or racing)
Pancreatitis acute (sudden inflammation of pancreas)
Pruritus generalised (generalized itching)
Retroperitoneal haematoma (blood clot between the peritoneum and the posterior abdominal wall)

male:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Blood glucose decreased
Cardioversion
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Disease recurrence
Extrasystoles
Foot fracture
Gastritis (inflammation of stomach)
Influenza

What are the common drug interactions of Rythmol Sr and Nexium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Asthenia (weakness)
Disease recurrence
Drug effect decreased
Malaise (a feeling of general discomfort or uneasiness)
Pain
Presyncope

60+:

Chronic kidney disease
Nephrogenic anaemia (anaemia due to kidney disease)
Abdominal tenderness
Abnormal behaviour
Angina pectoris (chest pain due to ischemia of the heart muscle)
Back pain
Blood glucose decreased
Cardioversion
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Dyspepsia (indigestion)

What are the existing conditions these people have? *

High Blood Cholesterol: 3 people, 14.29%
High Blood Pressure: 3 people, 14.29%
Stress And Anxiety: 2 people, 9.52%
Pain: 2 people, 9.52%
Asthma: 2 people, 9.52%
Chest Pain: 2 people, 9.52%
Colitis (inflammation of colon): 2 people, 9.52%
Cough: 2 people, 9.52%
Depression: 2 people, 9.52%
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters): 2 people, 9.52%

* Approximation only. Some reports may have incomplete information.

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