Rythmol and Humalog drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Rythmol (propafenone hydrochloride) and Humalog (insulin lispro recombinant). Common drug interactions include multiple injuries among females and colitis among males.

The phase IV clinical study analyzes what interactions people have when they take Rythmol and Humalog. It is created by eHealthMe based on reports of 35 people who take the same drugs from the FDA, and is updated regularly.

What is Rythmol?

Rythmol has active ingredients of propafenone hydrochloride. It is often used in atrial fibrillation/flutter. eHealthMe is studying from 3,638 Rythmol users. Check the latest studies of Rythmol.

What is Humalog?

Humalog has active ingredients of insulin lispro recombinant. It is often used in diabetes. eHealthMe is studying from 137,127 Humalog users. Check the latest studies of Humalog.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 20, 2026

35 people who take Rythmol and Humalog together, and have interactions are studied.

What are the common drug interactions of Rythmol and Humalog, by gender? *:

female:

Multiple injuries
Renal failure acute (rapid kidney dysfunction)
Vomiting
Renal failure (kidney dysfunction)
Viral infection
Weight decreased
Abdominal pain
Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
Diarrhoea
Dyspnoea paroxysmal nocturnal (respiratory distress that awakens patients from sleep)

male:

Colitis (inflammation of colon)
Cough
Blood bilirubin increased
Blood calcium increased
Blood creatinine increased
Blood potassium increased
Blood pressure inadequately controlled
Blood triglycerides increased
Blood urea increased
Blood urea nitrogen/creatinine ratio increased

What are the common drug interactions of Rythmol and Humalog, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Renal tubular necrosis (death of kidney tubules)
Syncope (loss of consciousness with an inability to maintain postural tone)
Abdominal pain
Anxiety
Asthenia (weakness)
Blood thyroid stimulating hormone decreased
Chest discomfort
Chest pain
Diabetic nephropathy (diabetic kidney disease)
Fluid overload (too much fluid in the blood)

60+:

Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Pneumonia
Bruxism (habitual grinding of the teeth, typically during sleep)
Cardiac failure congestive
Choking (mechanical obstruction of the flow of air from the environment into the lungs)
Cold sweat
Colitis (inflammation of colon)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cough
Decreased appetite

What are the existing conditions these people have? *

Immunodeficiency Common Variable: 8 people, 22.86%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 4 people, 11.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 11.43%
Pain: 3 people, 8.57%
Multiple Myeloma (cancer of the plasma cells): 3 people, 8.57%
Constipation: 3 people, 8.57%
Adverse Event: 3 people, 8.57%
Malignant Melanoma (skin cancer rises from melancytes): 2 people, 5.71%
High Blood Pressure: 2 people, 5.71%
Depression: 2 people, 5.71%

* Approximation only. Some reports may have incomplete information.

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